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Review
. 2024 Dec 27;17(1):67.
doi: 10.3390/nu17010067.

Common Questions and Misconceptions About Energy Drinks: What Does the Scientific Evidence Really Show?

Affiliations
Review

Common Questions and Misconceptions About Energy Drinks: What Does the Scientific Evidence Really Show?

Jose Antonio et al. Nutrients. .

Abstract

Energy drinks are a commonly consumed beverage, and studies suggest a possible performance-enhancing effect. A Google Scholar search using the keywords "energy drinks" and "exercise" yields numerous results, underscoring the voluminous research on this topic. However, there are questions regarding the effectiveness and safety of energy drinks. These questions include, but are not limited to: (1) What are the main active ingredients in energy drinks? (2) Do energy drinks assist in weight management? (3) Do energy drinks enhance aerobic performance? (4) Do energy drinks enhance athletic speed? (5) Do energy drinks improve reaction time? (6) Do energy drinks enhance lean tissue mass? (7) Can energy drinks improve cognitive performance? (8) Does the acute consumption of energy drinks elevate resting energy expenditure? (9) Is there any evidence to suggest that energy drinks are more effective than an identical serving of caffeine alone? (10) Are there sex differences in the response to energy drink consumption? (11) Do energy drinks affect sleep or sleepiness? (12) Should pregnant women avoid energy drinks? (13) Do energy drinks adversely affect cardiovascular function? (14) Does consuming energy drinks cause brain damage? (15) What are other safety considerations regarding energy drinks? (16) Is there any evidence to suggest that energy drinks are more effective than an identical serving of caffeine alone? (17) If caffeine is the main active ingredient in energy drinks and coffee, why is there a discrepancy in the adverse events reported for each? To address these questions, we performed an evidence-based scientific evaluation of the literature on energy drink supplementation.

Keywords: caffeine; ergogenic aids; supplements.

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Conflict of interest statement

J.A. is the CEO of the International Society of Sports Nutrition (ISSN), a 501c3 academic nonprofit. The ISSN receives grants from companies that sell, market, and manufacture protein-containing sports nutrition products, including energy drinks. Additionally, J.A. serves on the advisory board of CREATE, Bear Balanced, and Liquid Youth. S.M.A. has received grants to evaluate the effects of dietary supplements, including caffeine and caffeine derivatives, serves or has served on scientific advisory boards for sport nutrition companies, has been a paid consultant for a coffee company, and holds patents for an ingredient used in a performance coffee product. C.M.K. has received and continues to receive funding from nutrition companies to conduct scientific studies related to exercise and nutrition. In addition, he also serves in a consulting and advisory capacity for different dietary supplement brands or manufacturers that sell products or ingredients in areas related to sports and active nutrition. D.G.C. has conducted industry-sponsored research involving caffeinated energy drinks; additionally, he serves as an expert witness/consultant in legal cases involving caffeinated energy drinks. G.E. is currently a scientific advisory board member for the National Academy of Sports Medicine and has previously been a scientific advisor and/or board of director/member for several dietary supplement companies, including energy drinks. D.F. has previously conducted studies on energy drinks. S.F. is a scientific advisor for Bear Balanced, a company that sells creatine products. S.F. has received creatine donations for scientific studies. S.F. is a sports nutrition advisor for the ISSN. A.R.J. has consulted with and received external funding from companies that sell certain dietary ingredients and has received remuneration from companies for delivering scientific presentations at conferences. A.R.J. also writes for online and other media outlets on topics related to exercise and nutrition. In addition, A.R.J. serves on the Scientific Advisory Board for Alzchem. D.S.K. declares in the past, he has worked on clinical trials with respect to energy drinks and common ingredients used in “pre-workouts”. M.N. has no conflict in terms of financial or business interests related to the topic of this manuscript. He has served as a paid consultant for industry; has received honoraria for writing lay articles and other media about sports nutrition/exercise performance. J.S. has, for the past 30 years, received grants and contracts to research dietary supplements, served as a paid consultant for industry, and received honoraria for speaking at conferences and writing lay articles about sports nutrition ingredients and topics. M.S. is the Director of the European Society of Preventive Medicine (ESPM), a registered charity in the United Kingdom. ESPM does receive grants from companies in the biotech and medical industry. All other authors have no COIs to declare.

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