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Review
. 2024 Dec 27;17(1):54.
doi: 10.3390/cancers17010054.

Metabolic-Modulating Effects of Radiation: Undetectable Yet Deadly-A Review on Radiotherapy

Francesco Fiorica  1 , Umberto Tebano  1 , Giuseppe Napoli  1 , Antonella Franceschetto  1 , Marco Muraro  1 , Carlotta Giorgi  2 , Paolo Pinton  2
Affiliations
Review

Metabolic-Modulating Effects of Radiation: Undetectable Yet Deadly-A Review on Radiotherapy

Francesco Fiorica et al. Cancers (Basel). .

Abstract

From a cancer-centric perspective, radiotherapy has been primarily viewed as a localised treatment modality, targeting cancer tissues with ionising radiation to induce DNA damage and cell death [...].

Keywords: Metabolic cancer pathway and radiotherapy; alternative radiation cell killing; radiation synergism.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Radiation induces a metabolic vulnerability in cells due to the Warburg effect.
Figure 2
Figure 2
Radiation induces a metabolic vulnerability in cells, causing lipid synthesis.
Figure 3
Figure 3
Radiation induces a metabolic vulnerability in amino acid pathways.
See this image and copyright information in PMC

References

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