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. 2025 Jan;23(1):36-38.
doi: 10.1016/j.jtha.2024.10.006.

Platelets welcome a new protein disulfide isomerase family member

Robert Flaumenhaft  1
Affiliations

Platelets welcome a new protein disulfide isomerase family member

Robert Flaumenhaft. J Thromb Haemost. 2025 Jan.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interests R.F. is a founder and consultant for Platelet Diagnostics. Beth Israel Deaconess Medical Center manages the interests of R.F.

Figures

Figure.
Figure.. Domain structure of TMX4.
TMX4 is a transmembrane thiol isomerase that contains a CPSC active site motif within a single thioredoxin domain. It enters the ER by virtue of its signal sequence and contains a RQR retention sequence to maintain it there. TMX4 undergoes both N-glycosylation of its extracellular domain and phosphorylation of its cytoplasmic domain.
See this image and copyright information in PMC

Comment on

References

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