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. 1985 Apr;48(1):260-2.
doi: 10.1128/iai.48.1.260-262.1985.

Large plasmids associated with virulence in Shigella species have a common function necessary for epithelial cell penetration

H Watanabe, A Nakamura

Large plasmids associated with virulence in Shigella species have a common function necessary for epithelial cell penetration

H Watanabe et al. Infect Immun. 1985 Apr.

Abstract

Large plasmids (120 to 140 megadaltons) associated with virulence of Shigella sonnei, S. flexneri 2a and S. dysenteriae 1 were transferred from each strain into Escherichia coli K-12 and avirulent S. flexneri 1b strains by ampicillin transposon (Tn1)-mediated conduction. Strains with the virulence plasmid could penetrate tissue culture cells irrespective of the original host of the plasmid.

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