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Review
. 1979 Dec;2(6):238-42.
doi: 10.1159/000214623.

[(Management of acute toxicity after high dose methotrexate therapy)]

[Article in German]
C Urban, I Mutz, R Kotz, K Krisch
Review

[(Management of acute toxicity after high dose methotrexate therapy)]

[Article in German]
C Urban et al. Onkologie. 1979 Dec.

Abstract

A 13-year-old girl with osteosarcoma and pulmonary metastases developed life-threatening renal toxicity, encephalopathy, and bone marrow failure following high dose methotrexate therapy. After successful treatment, high dose methotrexate therapy was continued without further problems. Recommendations for the prevention and the current management of methotrexate toxicity are discussed.

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