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Review
. 2024 Dec 17;4(1):101465.
doi: 10.1016/j.jacadv.2024.101465. eCollection 2025 Jan.

Dietary Interventions in Heart Failure With Preserved Ejection Fraction: A Scoping Review

Hayley E Billingsley  1 , Salvatore Carbone  2   3 , Elissa Driggin  4 , Dalane W Kitzman  5 , Scott L Hummel  1   6
Affiliations
Review

Dietary Interventions in Heart Failure With Preserved Ejection Fraction: A Scoping Review

Hayley E Billingsley et al. JACC Adv. .

Abstract

Patients with heart failure with preserved ejection fraction (HFpEF) are burdened by multiple diet-sensitive comorbidities, including obesity and malnutrition. Despite this, a low percentage of patients with HFpEF have been enrolled in dietary intervention trials in heart failure and few dietary interventions have been conducted in HFpEF exclusively. This scoping review will examine available evidence regarding dietary interventions in patients with HFpEF, highlight existing gaps in knowledge, and discuss emerging dietary therapies in this population.

Keywords: dietary patterns; dietary supplements; heart failure with preserved ejection fraction; malnutrition; sodium restriction; weight loss.

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Conflict of interest statement

Dr Billingsley was supported by T32 Training Grant 5T32AG062403-04. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

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Graphical abstract
Central Illustration
Central Illustration
Optimizing Nutrition Care in Patients With Heart Failure With Preserved Ejection Fraction Patients with heart failure with preserved ejection fraction (HFpEF) have high rates of obesity, sarcopenia, and malnutrition. While most patients can likely benefit from an optimized dietary pattern such as dietary approaches to stop hypertension (DASH) or the mediterranean diet (MedDiet), dietary interventions should be personalized to the unique needs of the individual. GLP = glucagon-like peptide.
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