Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Dec 13;16(12):e75650.
doi: 10.7759/cureus.75650. eCollection 2024 Dec.

Severe Malaria Due to Imported Plasmodium ovale: A Case Report From New York

Affiliations
Case Reports

Severe Malaria Due to Imported Plasmodium ovale: A Case Report From New York

Farshad Bagheri et al. Cureus. .

Abstract

Malaria is highly prevalent in West and Central Africa. In the United States, most reported cases are due to immigration from endemic regions. Severe malaria caused by Plasmodium ovale is rare. This case report details a young, previously healthy male traveler from North Central Africa who presented to the emergency department with septic shock, later diagnosed as P. ovale malaria. This report aims to raise awareness among healthcare workers about the potential for P. ovale to cause severe malaria and to emphasize the importance of prompt diagnosis and treatment.

Keywords: : malaria; endemic malaria; hypnozoite; imported malaria; malaria treatment; medical intensive care unit (micu); plasmodium ovale; primaquine; septic shock [ss]; travel history.

PubMed Disclaimer

Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Picture of Ventral side of Right Foot
There is a pigmented rash scattered across the sole of the right foot.
Figure 2
Figure 2. CT scan of the chest
This image shows interstitial edema in both lungs and bilateral pleural effusions.
Figure 3
Figure 3. CT scan of the Abdomen and Pelvis
This image depicts slight ascites, periportal edema in the liver, pericholecystic edema, hepatomegaly, and splenomegaly.
Figure 4
Figure 4. CT scan of the abdomen and pelvis
This image depicts generalized edema, slight ascites, periportal edema in the liver, pericholecystic edema, hepatomegaly, and splenomegaly.

References

    1. Plasmodium ovale: parasite and disease. Collins WE, Jeffery GM. Clin Microbiol Rev. 2005;18:570–581. - PMC - PubMed
    1. Imported malaria in countries where malaria is not endemic: a comparison of semi-immune and nonimmune travelers. Mischlinger J, Rönnberg C, Álvarez-Martínez MJ, et al. Clin Microbiol Rev. 2020;33 - PMC - PubMed
    1. Malaria surveillance - United States, 2018. Mace KE, Lucchi NW, Tan KR. MMWR Surveill Summ. 2022;71:1–35. - PMC - PubMed
    1. Decrypting the complexity of the human malaria parasite biology through systems biology approaches. Chahine Z, Le Roch KG. Front Syst Biol. 2022;2 - PMC - PubMed
    1. Votypka J, Modry D, Oborník M, Slapeta J, Julius L. Cham: Springer International Publishing; 2016. Apicomplexa.

Publication types

LinkOut - more resources