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. 2024 Sep-Nov;28(3-4):224-234.
doi: 10.1080/13651501.2024.2446777. Epub 2025 Jan 14.

Adolescents with first-episode psychosis and clinical high risk in the Province of Ferrara: an audit on the implementation of a specialised early intervention program

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Free article

Adolescents with first-episode psychosis and clinical high risk in the Province of Ferrara: an audit on the implementation of a specialised early intervention program

Vittoria Magnabosco et al. Int J Psychiatry Clin Pract. 2024 Sep-Nov.
Free article

Abstract

Objective: The first-episode psychosis (FEP) and clinical high-risk (CHR) team within the child and adolescent mental health (CAMH) service receives referrals by psychiatric units, CAMH service, schools, and general practitioners. This audit evaluated the implementation of the FEP-CHR team in Ferrara, Italy.

Methods: The FEP-CHR team provides standardised assessment and up to 2-year individualised treatment including pharmacological prescription, cognitive-behavioral psychotherapy, and vocational activities. Data regarding access and pathways to care, assessment, and outcome of all patients admitted to this service from January 2019 to June 2023 were analysed. Descriptive statistics were reported and discussed.

Results: The service admitted 29 patients (19 FEP, 10 CHR), mostly females. FEP referrals primarily came from families via general practitioners, while half of CHR patients were already receiving CAMH care. One in three in the total sample had psychiatric hospitalisation during treatment. At discharge, most transitioned to usual or specialised mental health care and five patients achieved full recovery.

Conclusions: The audit revealed a lower-than-expected incidence rate, a sub-optimal adherence to the standardised assessment, and a need for improved outcome monitoring. It promoted quality improvement initiatives including professional training to improve psychiatric differential diagnosis, drug prescribing, and transition to adult psychiatric services.

Keywords: Adolescents; clinical high risk; early intervention; first-episode psychosis; service implementation.

Plain language summary

The female sex prevailed among CHR individuals suggesting a different help-seeking behaviour and clinical presentation compared to the male sex in adolescents.A significant portion of CHR and FEP patients were already receiving care prior to their psychosis diagnosis, highlighting the importance of training the community to identify early signs of psychosis.The findings prompted initiatives to improve service quality, including professional training to refine psychiatric differential diagnosis, optimise pharmacological prescribing practices, and facilitate smoother transitions to adult mental health services.

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