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Case Reports
. 2022 Dec 1;12(4):232-237.
doi: 10.4103/jmau.jmau_67_22. eCollection 2024 Oct-Dec.

Peripheral Fibro-osseous Lesion: An Institutional Study of 38 Cases

Apeksha Jain  1 , Rishikesh Mehta  1 , Treville Pereira  1 , Rutuja Gajanan Vidhale  1 , A K Anjali  1 , Subraj J Shetty  1
Affiliations
Case Reports

Peripheral Fibro-osseous Lesion: An Institutional Study of 38 Cases

Apeksha Jain et al. J Microsc Ultrastruct. .

Abstract

Background: The term "peripheral fibro-osseous lesion (PFOL)" is used relatively for common gingival lesions characterized histologically by hypercellular connective tissue showing either new bone-like formations or cementum-like substance and rarely dystrophic calcifications. These lesions are closely related to the other fibro-osseous lesions such as cemental periapical dysplasia, fibrous dysplasia, and other calcifying odontogenic cysts and tumors. The etiology is unknown, but certain authors suggest plaque, dental calculus, and ill-fitting dentures which might be the irritating agents causing irritation to the periodontal ligament which leads to such reactive growth.

Aim: The main aim of the present study is to present the clinicopathological features of a series of cases from the institute of D. Y Patil Deemed to be University, School of Dentistry.

Materials and methods: A total of 38 cases were evaluated over a period of 20 years. The age, size, gender, location, signs and symptoms, irritating agents, and the type of mineralized tissue present in the lesions were evaluated. Modified Gallego's Stain was performed to identify the hard tissues.

Results: The age range of patients (males = 23, females = 15) was 6-71 years (mean = 29.842 years). The lesions had more predisposition for males (males = 60.53%, females = 39.47%). The occurrence of the lesion was more in maxilla with 65% of cases occurring in anterior region.

Conclusion: According to the present study, PFOL has a slight predominance in males, with the mean age being 29.842 years with the highest occurrence in the anterior maxillary arch.

Keywords: Periodontal ligament; peripheral cementifying fibroma; peripheral cemento-ossifying fibroma; peripheral fibro-osseous lesions; peripheral ossifying fibroma.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Clinical picture of POF in a 14 year old male showing gingival overgrowth. POF: Peripheral ossifying fibroma
Figure 2
Figure 2
H and E stained section under ×100 showing fibrillar connective tissue stroma with new bone formation. H and E: Hematoxylin and eosin
Figure 3
Figure 3
(a) H and E stained section under ×400 depicting new bone formation. (b) H and E stained section under ×400 showing plump fibroblasts in fibrillar connective tissue stroma. H and E: Hematoxylin and eosin
Figure 4
Figure 4
(a) Modified Gallego’s stain showing dark red depositions of cementum-like structure (b) Modified Gallego’s stain showing green trabecular regions depicting bone
See this image and copyright information in PMC

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