Blood Eosinophil Count Stability in COPD and the Eosinophilic Exacerbator Phenotype
- PMID: 39813681
- PMCID: PMC12091026
- DOI: 10.1164/rccm.202407-1287RL
Blood Eosinophil Count Stability in COPD and the Eosinophilic Exacerbator Phenotype
Keywords: COPD; Eosinophils; Exacerbations; Type II inflammation.
References
-
- Bafadhel M, Peterson S, De Blas MA, Calverley PM, Rennard SI, Richter K, et al. Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials. Lancet Respir Med . 2018;6:117–126. - PubMed
-
- Global Initiative for Chronic Obstructive Lung Disease. Global Initiative for Chronic Obstructive Lung Disease; 2024. https://goldcopd.org/2024-gold-report/
-
- Tan WC, Bourbeau J, Nadeau G, Wang W, Barnes N, Landis SH, et al. High eosinophil counts predict decline in FEV1: results from the CanCOLD study. Eur Respir J . 2021;57:2000838. - PubMed
-
- Bhatt SP, Rabe KF, Hanania NA, Vogelmeier CF, Cole J, Bafadhel M, et al. BOREAS Investigators Dupilumab for COPD with type 2 inflammation indicated by eosinophil counts. N Engl J Med . 2023;389:205–214. - PubMed
-
- Van Rossem I, Hanon S, Verbanck S, Vanderhelst E. Blood eosinophil counts in chronic obstructive pulmonary disease: adding within-day variability to the equation. Am J Respir Crit Care Med . 2022;205:727–729. - PubMed
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