Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 Mar;48(3):1176-1178.
doi: 10.1038/s41440-024-02092-w. Epub 2025 Jan 16.

Redefining glomerular hyperfiltration: pathophysiology, clinical implications, and novel perspectives

Affiliations
Editorial

Redefining glomerular hyperfiltration: pathophysiology, clinical implications, and novel perspectives

Seiji Kishi. Hypertens Res. 2025 Mar.
No abstract available

Keywords: Aging; GFR; Hyperfiltration; Impaired glucose tolerance; Obesity.

PubMed Disclaimer

Conflict of interest statement

Compliance with ethical standards. Conflict of interest: The author declares no competing interests.

Comment on

References

    1. Cortinovis M, Perico N, Ruggenenti P, Remuzzi A, Remuzzi G. Glomerular hyperfiltration. Nat Rev Nephrol. 2022;18:435–51. - DOI - PubMed
    1. Kanbay M, Copur S, Bakir CN, Covic A, Ortiz A, Tuttle KR. Glomerular hyperfiltration as a therapeutic target for CKD. Nephrol Dial Transplant. 2024;39:1228–38. - DOI - PubMed
    1. Kanbay M, Ertuglu LA, Afsar B, Ozdogan E, Kucuksumer ZS, Ortiz A, et al. Renal hyperfiltration defined by high estimated glomerular filtration rate: A risk factor for cardiovascular disease and mortality. Diabetes Obes Metab. 2019;21:2368–83. - DOI - PubMed
    1. Neugarten J, Acharya A, Silbiger SR. Effect of gender on the progression of nondiabetic renal disease: a meta-analysis. J Am Soc Nephrol. 2000;11:319–29. - DOI - PubMed
    1. Cherney DZ, Kanbay M, Lovshin JA. Renal physiology of glucose handling and therapeutic implications. Nephrol Dial Transplant. 2020;35:i3–12. - DOI - PubMed - PMC

LinkOut - more resources