Promotion of Cardiovascular Health in Africa: The Alliance for Medical Research in Africa (AMedRA) Expert Panel

Mame Madjiguene Ka^{1

2}, Ngone Diaba Gaye^{1

3}, Dzifa Ahadzi⁴, Carissa M Baker-Smith^{5

6

7}, Serigne Cheikh Tidiane Ndao², Vivien Wambugu^{1

8}, Gurbinder Singh¹, Khadidiatou Gueye^{1

9}, Daouda Seck^{1

10}, Khadidiatou Dia², Norrina Bai Allen¹¹, Awa Ba^{1

12}, Waly Niang Mboup², Rabab Yassine², Pape Momar Guissé², Malick Anne^{1

13}, Fatou Aw¹⁴, Serigne Mor Bèye¹⁵, Marguerite Tening Diouf¹⁶, Mor Diaw¹⁷, Jamal Belkhadir^{1

18}, Issa Wone¹⁹, Jamal Eddine Kohen^{1

20}, Maïmouna Ndour Mbaye^{1

21}, Aliou Alassane Ngaide²¹, Elisabeth Alice Liyong^{1

22}, Ndeye Marième Sougou²³, Mathias Lalika²⁴, Boni Maxime Ale^{25

26

27

28}, Lamin Jaiteh^{1

29}, Demeke Mekonnen^{1

30}, Fred Bukachi^{31

32}, Thiess Lorenz^{33

34

35}, Kauthrah Ntabadde^{36

37}, Warner Mampuya³⁸, Dismand Houinato^{39

40}, David Lagoro Kitara^{1

41}, Abdoul Kane^{15

20}, Sidy Mouhamed Seck^{1

42}, Ibrahima Socé Fall^{1

43}, Léon Tshilolo^{1

44

45}, Abdoulaye Samb^{1

17}, Mayowa Owolabi^{46

47

48

49

50}, Massamba Diouf⁵¹, Roberta Lamptey^{52

53}, André Pascal Kengne^{54

52}, Pasquale Maffia^{55

56

57}, Gari D Clifford⁵⁸, Elisabeth Lilian Pia Sattler^{1

59}, Mouhamed Chérif Mboup², Modou Jobe^{1

60}, Bamba Gaye^{1

17

61}

Affiliations

¹ Alliance for Medical Research in Africa, Dakar, Senegal.
² Department of Cardiology, Principal Hospital of Dakar, Dakar, Senegal.
³ Ibra Mamadou Wane Medical Center, Department of Cardiac Rehabilitation, Dakar, Senegal.
⁴ Department of Medicine, Tamale Teaching Hospital, Tamale, Ghana.
⁵ Center for Cardiovascular Research and Innovation, Nemours Cardiac Center, Nemours Children's Health, Wilmington, Delaware, USA.
⁶ Preventive Cardiology Program, Nemours Cardiac Center, Nemours Children's Health, Wilmington, Delaware, USA.
⁷ Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
⁸ Yale School of Medicine, New Haven, Connecticut, USA.
⁹ Department of Cardiology, University Hospital of Fann, Dakar, Senegal.
¹⁰ Direction de la Santé Publique, Institut Pasteur de Dakar, Dakar, Sénégal.
¹¹ Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
¹² Laboratoire de physiologie, département de médecine, UFR Santé et Développement Durable, Université Alioune Diop de Bambey, Diourbel, Senega.
¹³ Division of Non-Communicable Diseases, Ministry of Health and Social Action of Senegal, Dakar, Senegal.
¹⁴ Faculty of Medicine, Pharmacy and Odontostomatology, Cheikh Anta Diop University, Dakar, Senegal.
¹⁵ Service de Cardiologie, Centre Hospitalier Régional de Saint-Louis, Saint-Louis, Senegal.
¹⁶ Department of Cardiology, Dalal Jamm Hospital, Dakar, Senegal.
¹⁷ Department of Physiology, Cheikh Anta Diop University, Dakar, Senegal.
¹⁸ Moroccan League for the Fight Against Diabetes, IDF Middle East and North Africa, Rabat, Morocco.
¹⁹ Département des Sciences de la Santé, Université Assane Seck de Ziguinchor, Ziguinchor, Senegal.
²⁰ Regional Council for the Order of Physicians, Fez-Meknes Region, Morocco.
²¹ Department of Internal Medicine and Specialties, Cheikh Anta Diop University of Dakar, Dakar, Senegal.
²² Department of Research Likak Research, Dakar, Senegal.
²³ Department of Public Health, University of Cheikh Anta Diop, Dakar, Senegal.
²⁴ Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
²⁵ Holo Global Health Research Institute, Cotonou, Benin.
²⁶ Health Data Acumen, Nairobi, Kenya.
²⁷ Institute of Tropical and Infectious Diseases, University of Nairobi, Nairobi, Kenya.
²⁸ School of Public Health, MOI University, Eldoret, Kenya.
²⁹ Department of Internal Medicine, Edward Francis Small Teaching Hospital/School of Medicine & Allied Health Sciences, University of the Gambia Banjul, Gambia.
³⁰ Department of Pediatrics and Child Health, St. Peter Specialized Hospital, Addis Ababa, Ethiopia.
³¹ Africa-Europe Cluster of Research Excellence (CoRE) in Non-Communicable Diseases & Multimorbidity, African Research Universities Alliance ARUA & The Guild, Nairobi, Kenya.
³² Department of Medical Physiology, Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya.
³³ Center for Population Health Innovation, University Heart and Vascular Center Hamburg, Hamburg, Germany.
³⁴ University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
³⁵ The German Center for Cardiovascular Research (DZHK) Partner Site Hamburg-Kiel-Lübeck, Hamburg, Germany.
³⁶ Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, USA.
³⁷ Welch Prevention Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins, Baltimore, USA.
³⁸ Service de cardiologie, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada.
³⁹ Laboratory of Chronic and Neurologic Diseases Epidemiology, LEMACEN, Doctoral School of Health Sciences, University of Abomey-Calavi, Cotonou, Benin.
⁴⁰ Département de Pédiatrie, Université Officielle de Mbujimayi (UOM), Kasai Oriental, Democratic Republic of the Congo.
⁴¹ Gulu University, Faculty of Medicine, Department of Surgery, Gulu, Uganda.
⁴² Faculty of Health Sciences and IRL-3189 ESS/UGB/UCAD/CNRS/CNRST/USTTB/ - University of Gaston Berger, Saint-Louis, Senegal.
⁴³ Division for Universal Health Coverage/Communicable Diseases, Noncommunicable Diseases and Mental Health, WHO Geneva, Switzerland.
⁴⁴ Institut de Recherche Biomédicale, CEFA- Monkole, Democratic Republic of the Congo.
⁴⁵ Département de Pédiatrie, Université Officielle de Mbujimayi (UOM), Democratic Republic of the Congo.
⁴⁶ Center for Genomics and Precision Medicine, University of Ibadan, Ibadan, Nigeria.
⁴⁷ Department of Medicine, University College Hospital, Ibadan, Nigeria.
⁴⁸ Africa-Europe CoRE in Non-Communicable Diseases & Multimorbidity, African Research Universities Alliance (ARUA) & The Guild of European Research-intensive Universities, Ibadan, Nigeria.
⁴⁹ Lebanese American University of Beirut, Lebanon.
⁵⁰ Blossom Specialist Medical Center, Ibadan, Nigeria.
⁵¹ Public Health Service, Institute of Dentistry and Stomatology, Faculty of Medicine, Pharmacy and Dentistry, Cheikh Anta Diop University of Dakar, Senegal.
⁵² Non-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
⁵³ Family Medicine Department, Korle Bu Teaching Hospital, Accra, Ghana.
⁵⁴ Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
⁵⁵ School of Infection & Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.
⁵⁶ Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Campania, Italy.
⁵⁷ Africa-Europe CoRE in Non-Communicable Diseases & Multimorbidity, African Research Universities Alliance (ARUA) & The Guild of European Research-intensive Universities, Glasgow, United Kingdom.
⁵⁸ Department of Biomedical Informatics, Emory University, Atlanta, Georgia, USA.
⁵⁹ Department of Clinical and Administrative Pharmacy, Department of Nutritional Sciences, University of Georgia, Athens, Georgia, USA.
⁶⁰ Medical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
⁶¹ Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, Georgia, USA.

PMID: 39817059
PMCID: PMC11733986
DOI: 10.1016/j.jacadv.2024.101376

Review

Promotion of Cardiovascular Health in Africa: The Alliance for Medical Research in Africa (AMedRA) Expert Panel

Mame Madjiguene Ka et al. JACC Adv. 2024.

. 2024 Nov 20;3(12):101376.

doi: 10.1016/j.jacadv.2024.101376. eCollection 2024 Dec.

Authors

Affiliations

¹ Alliance for Medical Research in Africa, Dakar, Senegal.
² Department of Cardiology, Principal Hospital of Dakar, Dakar, Senegal.
³ Ibra Mamadou Wane Medical Center, Department of Cardiac Rehabilitation, Dakar, Senegal.
⁴ Department of Medicine, Tamale Teaching Hospital, Tamale, Ghana.
⁵ Center for Cardiovascular Research and Innovation, Nemours Cardiac Center, Nemours Children's Health, Wilmington, Delaware, USA.
⁶ Preventive Cardiology Program, Nemours Cardiac Center, Nemours Children's Health, Wilmington, Delaware, USA.
⁷ Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
⁸ Yale School of Medicine, New Haven, Connecticut, USA.
⁹ Department of Cardiology, University Hospital of Fann, Dakar, Senegal.
¹⁰ Direction de la Santé Publique, Institut Pasteur de Dakar, Dakar, Sénégal.
¹¹ Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
¹² Laboratoire de physiologie, département de médecine, UFR Santé et Développement Durable, Université Alioune Diop de Bambey, Diourbel, Senega.
¹³ Division of Non-Communicable Diseases, Ministry of Health and Social Action of Senegal, Dakar, Senegal.
¹⁴ Faculty of Medicine, Pharmacy and Odontostomatology, Cheikh Anta Diop University, Dakar, Senegal.
¹⁵ Service de Cardiologie, Centre Hospitalier Régional de Saint-Louis, Saint-Louis, Senegal.
¹⁶ Department of Cardiology, Dalal Jamm Hospital, Dakar, Senegal.
¹⁷ Department of Physiology, Cheikh Anta Diop University, Dakar, Senegal.
¹⁸ Moroccan League for the Fight Against Diabetes, IDF Middle East and North Africa, Rabat, Morocco.
¹⁹ Département des Sciences de la Santé, Université Assane Seck de Ziguinchor, Ziguinchor, Senegal.
²⁰ Regional Council for the Order of Physicians, Fez-Meknes Region, Morocco.
²¹ Department of Internal Medicine and Specialties, Cheikh Anta Diop University of Dakar, Dakar, Senegal.
²² Department of Research Likak Research, Dakar, Senegal.
²³ Department of Public Health, University of Cheikh Anta Diop, Dakar, Senegal.
²⁴ Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
²⁵ Holo Global Health Research Institute, Cotonou, Benin.
²⁶ Health Data Acumen, Nairobi, Kenya.
²⁷ Institute of Tropical and Infectious Diseases, University of Nairobi, Nairobi, Kenya.
²⁸ School of Public Health, MOI University, Eldoret, Kenya.
²⁹ Department of Internal Medicine, Edward Francis Small Teaching Hospital/School of Medicine & Allied Health Sciences, University of the Gambia Banjul, Gambia.
³⁰ Department of Pediatrics and Child Health, St. Peter Specialized Hospital, Addis Ababa, Ethiopia.
³¹ Africa-Europe Cluster of Research Excellence (CoRE) in Non-Communicable Diseases & Multimorbidity, African Research Universities Alliance ARUA & The Guild, Nairobi, Kenya.
³² Department of Medical Physiology, Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya.
³³ Center for Population Health Innovation, University Heart and Vascular Center Hamburg, Hamburg, Germany.
³⁴ University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
³⁵ The German Center for Cardiovascular Research (DZHK) Partner Site Hamburg-Kiel-Lübeck, Hamburg, Germany.
³⁶ Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, USA.
³⁷ Welch Prevention Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins, Baltimore, USA.
³⁸ Service de cardiologie, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada.
³⁹ Laboratory of Chronic and Neurologic Diseases Epidemiology, LEMACEN, Doctoral School of Health Sciences, University of Abomey-Calavi, Cotonou, Benin.
⁴⁰ Département de Pédiatrie, Université Officielle de Mbujimayi (UOM), Kasai Oriental, Democratic Republic of the Congo.
⁴¹ Gulu University, Faculty of Medicine, Department of Surgery, Gulu, Uganda.
⁴² Faculty of Health Sciences and IRL-3189 ESS/UGB/UCAD/CNRS/CNRST/USTTB/ - University of Gaston Berger, Saint-Louis, Senegal.
⁴³ Division for Universal Health Coverage/Communicable Diseases, Noncommunicable Diseases and Mental Health, WHO Geneva, Switzerland.
⁴⁴ Institut de Recherche Biomédicale, CEFA- Monkole, Democratic Republic of the Congo.
⁴⁵ Département de Pédiatrie, Université Officielle de Mbujimayi (UOM), Democratic Republic of the Congo.
⁴⁶ Center for Genomics and Precision Medicine, University of Ibadan, Ibadan, Nigeria.
⁴⁷ Department of Medicine, University College Hospital, Ibadan, Nigeria.
⁴⁸ Africa-Europe CoRE in Non-Communicable Diseases & Multimorbidity, African Research Universities Alliance (ARUA) & The Guild of European Research-intensive Universities, Ibadan, Nigeria.
⁴⁹ Lebanese American University of Beirut, Lebanon.
⁵⁰ Blossom Specialist Medical Center, Ibadan, Nigeria.
⁵¹ Public Health Service, Institute of Dentistry and Stomatology, Faculty of Medicine, Pharmacy and Dentistry, Cheikh Anta Diop University of Dakar, Senegal.
⁵² Non-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
⁵³ Family Medicine Department, Korle Bu Teaching Hospital, Accra, Ghana.
⁵⁴ Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
⁵⁵ School of Infection & Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.
⁵⁶ Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Campania, Italy.
⁵⁷ Africa-Europe CoRE in Non-Communicable Diseases & Multimorbidity, African Research Universities Alliance (ARUA) & The Guild of European Research-intensive Universities, Glasgow, United Kingdom.
⁵⁸ Department of Biomedical Informatics, Emory University, Atlanta, Georgia, USA.
⁵⁹ Department of Clinical and Administrative Pharmacy, Department of Nutritional Sciences, University of Georgia, Athens, Georgia, USA.
⁶⁰ Medical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
⁶¹ Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, Georgia, USA.

PMID: 39817059
PMCID: PMC11733986
DOI: 10.1016/j.jacadv.2024.101376

Abstract

This proposed scientific statement is focused on providing new insights regarding challenges and opportunities for cardiovascular health (CVH) promotion in Africa. The statement includes an overview of the current state of CVH in Africa, with a particular interest in the cardiometabolic risk factors and their evaluation through metrics. The statement also explains the main principles of primordial prevention, its relevance in reducing noncommunicable disease and the different strategies that have been effective worldwide. Also, the statement addresses challenges for implementing primordial prevention strategies in Africa, such as socioeconomic, cultural, lifestyle, and environmental factors, and highlights the importance of adapting strategies to the context. Finally, the statement recommends fundamental approaches for promoting CVH with the help of various partnerships and the involvement of communities.

Keywords: Africa; cardiovascular health; diabetes; hypertension; obesity; primordial prevention.

PubMed Disclaimer

Conflict of interest statement

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

**Central Illustration**
Promoting Cardiovascular Primordial Prevention in Africa CVD = cardiovascular disease; EMF = endomyocardial fibrosis.

See this image and copyright information in PMC

References

1. Mensah G.A., Roth G.A., Fuster V. The global burden of cardiovascular diseases and risk factors: 2020 and beyond. J Am Coll Cardiol. 2019;74(20):2529–2532. doi: 10.1016/j.jacc.2019.10.009. - DOI - PubMed
1. Visseren F.L.J., Mach F., Smulders Y.M., et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies with the special contribution of the European Association of Preventive Cardiology (EAPC) Eur Heart J. 2021;42(34):3227–3337. doi: 10.1093/eurheartj/ehab484. - DOI - PubMed
1. Lloyd-Jones D.M., Allen N.B., Anderson C.A.M., et al. Life’s essential 8: updating and enhancing the American heart association’s construct of cardiovascular health: a presidential advisory from the American heart association. Circulation. 2022;146(5):e18–e43. doi: 10.1161/CIR.0000000000001078. - DOI - PMC - PubMed
1. Sliwa K., Wilkinson D., Hansen C., et al. Spectrum of heart disease and risk factors in a black urban population in South Africa (the Heart of Soweto Study): a cohort study. Lancet Lond Engl. 2008;371(9616):915–922. doi: 10.1016/S0140-6736(08)60417-1. - DOI - PubMed
1. Lassale C., Gaye B., Diop I.B., et al. Use of traditional medicine and control of hypertension in 12 African countries. BMJ Glob Health. 2022;7(6) doi: 10.1136/bmjgh-2021-008138. - DOI - PMC - PubMed

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Promotion of Cardiovascular Health in Africa: The Alliance for Medical Research in Africa (AMedRA) Expert Panel

Affiliations

Promotion of Cardiovascular Health in Africa: The Alliance for Medical Research in Africa (AMedRA) Expert Panel

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

Publication types

Grants and funding

LinkOut - more resources

Full Text Sources