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Review
. 2025 Jul;13(7):1518-1526.
doi: 10.1016/j.jaip.2024.12.042. Epub 2025 Jan 15.

Digital Health for Asthma Management: Electronic Medication Monitoring for Adherence as a Case Example

Affiliations
Review

Digital Health for Asthma Management: Electronic Medication Monitoring for Adherence as a Case Example

Heather Hoch De Keyser et al. J Allergy Clin Immunol Pract. 2025 Jul.

Abstract

Digital health is an umbrella term for components of health care using computer platforms, software, connectivity, and sensors to augment the recording, documentation, and communication of clinical information. The functions of digital health may be viewed in three domains: (1) the repository for patient information, (2) monitoring devices, and (3) communication tools. Monitoring devices have provided robust information as diagnostic and prognostic tools in office and hospital settings. In this review, as a case study, we will discuss the research and our direct clinical experience of electronic medication monitoring technology and the potential benefits to patient care, and the opportunities and perils encountered in using this approach for patients with moderate to severe asthma, including issues related to patient uptake and concerns for bias, impacts on the provider-patient relationship, and discussions regarding monitoring of rescue medication use in exacerbations. Additionally, although there is evidence for improvements in various aspects of patient care afforded by electronic medication monitoring, these devices have not yet seen widespread uptake in clinical settings, and we will discuss the steps needed to address these barriers and keep these important devices available for patient use in the future.

Keywords: Artificial intelligence; Asthma; Asthma biologics; Digital health; Electronic medication monitoring; Remote patient monitoring; Severe asthma.

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Conflict of interest statement

Heather De Keyser: Research reported in this publication was supported by the National Heart, Lung, And Blood Institute of the National Institutes of Health under Award Number K23HL146791. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

William Anderson has served on advisory boards for Regeneron and Sanofi. He has received program development grants from the Colorado Medicaid Supplemental Funding Program and the COPIC Medical Foundation.

David Stempel: Former employee of Propeller Health

Stanley J. Szefler has consulted for Eli Lilly, Regeneron and Sanofi and has received research support from the National Institutes of Health National Heart, Lung and Blood Institute (4UH3HL151297-04), Propeller Health 19-0752, Data Integration and Community Enhancement Center, and the Colorado Department of Public Health and Environment (CDPHE) Cancer, Cardiovascular and Pulmonary Disease Program.

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