Finding the right HARMONi-A
- PMID: 39830738
- PMCID: PMC11736612
- DOI: 10.21037/tlcr-24-864
Finding the right HARMONi-A
Keywords: Non-small cell lung cancer (NSCLC); epidermal growth factor receptor-mutant (EGFR-mutant); ivonescimab.
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tlcr.amegroups.com/article/view/10.21037/tlcr-24-864/coif). V.C.C.d.L. received a consulting fee from Roche; received honoraria for lectures, presentations, manuscript writing, and educational events from Roche Brasil, Amgen, MSD Brasil, BMS Brasil, Jassen, Daichii-Sankyo, Pfizer, and Astra Zeneca; and received financial support to attend scientific meetings and travels from Astra Zeneca, Roche, and Janssen. He also participated in advisory boards from Roche Brasil, Amgen, MSD Brasil, BMS Brasil, Jassen, Daichii-Sankyo, Pfizer, Astra-Zeneca, and Pfizer. H.C.F. has received payment or honoraria for lectures, presentations, speaker bureaus, or educational from MSD, Roche, Lilly, Pfizer, Takeda, BMS, Amgen, AstraZeneca, and Merck. Support for attending meetings or travel has been provided by BMS, MSD, Pfizer, Roche, AZ, Takeda, and Sanofi. He also participates in advisory boards for MSD, Pfizer, Lilly, Takeda, Roche, BMS, and Amgen. Additionally, his spouse works in the clinical research department at AstraZeneca. The authors have no other conflicts of interest to declare.
Comment on
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Ivonescimab Plus Chemotherapy in Non-Small Cell Lung Cancer With EGFR Variant: A Randomized Clinical Trial.JAMA. 2024 Aug 20;332(7):561-570. doi: 10.1001/jama.2024.10613. JAMA. 2024. PMID: 38820549 Free PMC article. Clinical Trial.
References
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- Mok T, Nakagawa K, Park K, et al. Nivolumab Plus Chemotherapy in Epidermal Growth Factor Receptor-Mutated Metastatic Non-Small-Cell Lung Cancer After Disease Progression on Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: Final Results of CheckMate 722. J Clin Oncol 2024;42:1252-64. 10.1200/JCO.23.01017 - DOI - PMC - PubMed
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