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. 2025 Jan 17;25(1):198.
doi: 10.1186/s12889-025-21444-w.

Cigarette smoking and perceived risk of cardiovascular disease in Iran

Affiliations

Cigarette smoking and perceived risk of cardiovascular disease in Iran

Fatemeh Zarghami et al. BMC Public Health. .

Abstract

Introduction: Studies have consistently demonstrated a strong link between cigarette smoking and an increased risk of cardiovascular diseases (CVD). On the other hand, studies have shown that most smokers do not have a real understanding of the cardiovascular health hazards of smoking. Therefore, the study aimed to determine the perceived risk of Myocardial Infarction (MI), Hypertension (HTN), and Stroke among current smokers in Iran.

Methods: This cross-sectional study was conducted between January and May 2023, and recruited 380 smokers by convenience sampling who smoked at least 100 cigarettes in their lifetime. The data were collected using three questionnaires (1) the questionnaire to assess the risk perception for MI, HTN, and Stroke, (2) the smoking stage of change questionnaire, and (3) the Fagerström Test for nicotine dependence (FTND). The CVD risk perception consisted of two parts, perceived susceptibility and perceived severity. Each part scores between 0 and 10 and finally gets a total score of 0-20. A score of zero indicated the lowest risk perception while a score of 20 indicated the highest risk perception. We examined the relationship between the demographic and smoking-related variables and the smokers' perceived risk of MI, stroke, and HTN by using multiple linear regression.

Findings: The mean age of participants was 35.57 ± 12.05 years, and 77.1% were male. The perceived risk score of MI was 10.68 ± 4.69 out of 20. The scores related to stroke and HTN were 10.00 ± 4.65 and 10.89 ± 4.73, respectively. Identified variables collectively contributed significantly to predicting the perceived risk of MI (p <.0001, Adj R-squared = 0.05%), stroke ( p <.0001, Adj R-squared = 0.08%), and HTN (p <.0001, Adj R-squared = 0.06%). We found that longer smoking duration [coefficient=-1.96 (95% CI= -3.91, - 0.09)] for 20-29 years and - 4.08 ( 95% CI= -6.70, -1.46 ) for 30 + years), older smoking age onset [coefficient=-2.10 ( 95% CI= -3.24, - 0.96 )] for 20 + years), and dual tobacco users [coefficient= -1. 04 (95% CI= -2.08, - 0.06)] were significantly associated with lower perceived risk for MI. We also found that longer smoking duration [coefficient=-2.23 (95% CI= -4.13, - 0.32)] for 20-29 years and - 5.01 (95% CI= -7.565734, -2.462361 ) for 30 + years), older smoking age onset [coefficient=-1.86 (95% CI= -2.970021, - 0.75 ] for 20 + years), and being male [coefficient= -2. 00, (95% CI= -3.53, - 0.47)] were significantly associated with lower perceived risk for stroke. We found that longer smoking duration (coefficient=-4.40 for 30 + years), older smoking age onset [coefficient=-2.02 (95% CI= -3.14, - 0.87,)] for 20 + years), and being dual users [coefficient=-1.36, 95% CI= -2.40, - 0.3241238)] were significantly associated with lower perceived risk for HTN.

Conclusion: The results of this study demonstrated a moderate perceived risk of participants to CVD. Also, the perceived risk decreases as the duration of smoking and the age for the smoking onset increases to 20 years and above. It seems necessary to carry out interventions to inform the public about the harms of smoking, especially for adolescents and young adults, and its risks in causing cardiovascular disease.

Keywords: Addiction; CVD; Cigarette smoking; Hypertension; Perceived risk; Stroke; Tobacco.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: All procedures were conducted following the Declaration of Helsinki (revised in 2013). The local ethics committee of Affiliated Golestan University of Medical Sciences approved all experimental protocols (Ethical number: IR.GOUMS.REC.1401.251). Informed consent was obtained from all subjects and/or their legal guardian(s). Consent for publication: Not Applicable. Competing interests: The authors declare no competing interests.

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References

    1. Barua RS, Ambrose JA, Srivastava S, DeVoe MC, Eales-Reynolds L-J. Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and upregulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells. Circulation. 2003;107(18):2342–7. - PubMed
    1. Dawber TR, Meadors GF, Moore FE Jr. Epidemiological approaches to heart disease: the Framingham Study. Am J Public Health Nations Health. 1951;41(3):279–86. - PMC - PubMed
    1. Salehi N, Janjani P, Tadbiri H, Rozbahani M, Jalilian M. Effect of cigarette smoking on coronary arteries and pattern and severity of coronary artery disease: a review. J Int Med Res. 2021;49(12):03000605211059893. - PMC - PubMed
    1. Golbidi S, Edvinsson L, Laher I. Smoking and endothelial dysfunction. Curr Vasc Pharmacol. 2020;18(1):1–11. - PubMed
    1. Kiriyama H, Kaneko H, Itoh H, Yoshida Y, Nakanishi K, Mizuno Y, et al. Effect of cigarette smoking on carotid artery atherosclerosis: a community-based cohort study. Heart Vessels. 2020;35:22–9. - PubMed

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