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Editorial
. 2025 Jan;28(1):e70085.
doi: 10.1111/1756-185X.70085.

Ankylosing Spondylitis and Cancer Risk

Shiuan-Tzuen Su  1   2 , Yung-Heng Lee  3   4   5   6 , Po-Cheng Shih  7   8 , James C-C Wei  8   9   10
Affiliations
Editorial

Ankylosing Spondylitis and Cancer Risk

Shiuan-Tzuen Su et al. Int J Rheum Dis. 2025 Jan.

Abstract

Chronic inflammation is a major characteristic of ankylosing spondylitis (AS) and is closely related to the mechanisms of cancer development. Persistent inflammatory responses can lead to DNA damage, gene mutations, and abnormal cell proliferation, all of which may increase the risk of cancer. We also explore the use of biologic therapy of AS and their potential cancer risks.

Keywords: TNFi; ankylosing spondylitis; cancer; inflammation.

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References

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