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Review
. 2025 Jan 21;151(3):257-271.
doi: 10.1161/CIRCULATIONAHA.124.068203. Epub 2025 Jan 21.

Survivorship After Cardiogenic Shock

Affiliations
Review

Survivorship After Cardiogenic Shock

Eric J Hall et al. Circulation. .

Abstract

Advances in critical care therapies for patients with cardiogenic shock (CS), including temporary mechanical circulatory support and multidisciplinary shock teams, have led to improved survival to hospital discharge, ranging from 60% to 70%. After their index hospitalization, however, survivors of CS may continue to face cardiac as well as extracardiac sequelae of these therapies and complications for years to come. Most studies in CS have focused primarily on survival, with limited data on long-term recovery measures among survivors. In other forms of critical illness, research indicates that many intensive care unit survivors experience impairments in multiple domains, such as cognitive function, physical ability, and mental health. These impairments, collectively referred to as Post-Intensive Care Syndrome, in turn impact survivors' quality of life and future prognosis. This review identifies unique aspects of CS-related survivorship, highlights lessons learned from other forms of critical illness, and outlines future research directions to determine specific strategies to enhance recovery and survivorship after CS.

Keywords: cognitive dysfunction; heart failure; intensive care units; shock, cardiogenic; survivorship.

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Conflict of interest statement

Dr Hall is supported by the National Institutes of Health/National Heart Lung and Blood Institute (grant 5T32HL125247-8). Dr Agarwal is supported by grants R01-HL153311 and R01-NS127959 from the National Institutes of Health. Dr Cullum reports serving as the Scientific Director of the Texas Alzheimer’s Research and Care Consortium and receiving royalties from the Texas Functional Living Scale, published by Pearson, Inc. Dr Ely reports receiving research funding from the National Institutes of Health and the VA. The other authors report no relevant disclosures.

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