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Review
. 2025:187:147-193.
doi: 10.1007/978-3-031-68827-0_12.

Nucleic Acids and Electrical Signals

Colin D McCaig  1
Affiliations
Review

Nucleic Acids and Electrical Signals

Colin D McCaig. Rev Physiol Biochem Pharmacol. 2025.

Abstract

Nucleic acids are highly charged, and electrical forces are involved heavily in how our DNA is compacted and packaged into such a small space, how chromosomes are formed, and how DNA damage is repaired. In addition, electrical forces are crucial to the formation of non-canonical DNA structures called G-Quadruplexes which play multiple biological roles.

Keywords: Cell cycle; Chromatid; Chromosome behaviour; Condensin; DNA repair; DNA replication; G-quadruplexes; Nucleic acids; Telomere.

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