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. 2024 Dec 22;16(12):e76198.
doi: 10.7759/cureus.76198. eCollection 2024 Dec.

Outcomes of Coronary Artery Bypass Grafting in Patients With Impaired Left Ventricular Function and the Role of Preoperative Myocardial Viability

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Outcomes of Coronary Artery Bypass Grafting in Patients With Impaired Left Ventricular Function and the Role of Preoperative Myocardial Viability

Muhammad Aasim et al. Cureus. .

Abstract

Background Coronary artery bypass grafting (CABG) improves outcomes in patients with ischemic left ventricular (LV) dysfunction, but accurate patient selection remains critical. Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging aids in assessing myocardial viability, a key predictor of surgical outcomes. This study aimed to evaluate the impact of myocardial viability on postoperative outcomes in patients undergoing CABG. Methods This was a single-center prospective analysis of clinical outcomes in 37 patients with impaired LV function (mean ejection fraction: 35.59%); myocardial viability was assessed using LGE-CMR prior to CABG. Patient demographics, perioperative details, and short-term outcomes, including in-hospital mortality and recovery metrics, were analyzed. Results Patients exhibited high myocardial viability (mean: 88.16%), with an average of 2.35 non-viable segments. In-hospital mortality was 5.4% (n=2), and the mean hospital stay was six days. Patients with greater viability demonstrated better recovery and fewer complications. Multivessel coronary artery disease was prevalent (94.6%, n=35), with tailored graft configurations addressing individual anatomical and disease complexities. Conclusion LGE-CMR is a valuable tool for predicting outcomes in ischemic LV dysfunction. Myocardial viability strongly correlates with improved surgical recovery, highlighting the importance of integrating LGE-CMR into preoperative decision-making. Further studies are required to explore the long-term impact of myocardial viability on treatment outcomes and quality of life.

Keywords: cardiac magnetic resonance (cmr) imaging; coronary artery bypass grafting (cabg); echocardiography; ischemic left ventricular dysfunction; late gadolinium enhancement (lge); myocardial viability.

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Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Institutional Research and Ethical Committee, Medical Teaching Institute - Hayatabad Medical Complex issued approval 1960. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

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References

    1. Current medical therapy for advanced heart failure. Gheorghiade M, Cody RJ, Francis GS, McKenna WJ, Young JB, Bonow RO. Am Heart J. 1998;135:231–248. - PubMed
    1. Results of coronary artery surgery in patients with poor left ventricular function (CASS) Alderman EL, Fisher LD, Litwin P, et al. Circulation. 1983;68:785–795. - PubMed
    1. Late results of surgical and medical therapy for patients with coronary artery disease and depressed left ventricular function. Pigott JD, Kouchoukos NT, Oberman A, Cutter GR. J Am Coll Cardiol. 1985;5:1036–1045. - PubMed
    1. Coronary artery bypass grafting in patients with poor ventricular function. Christakis GT, Weisel RD, Fremes SE, Ivanov J, David TE, Goldman BS, Salerno TA. J Thorac Cardiovasc Surg. 1992;103:1083–1092. - PubMed
    1. Coronary artery bypass grafting in severe left ventricular dysfunction: excellent survival with improved ejection fraction and functional state. Elefteriades JA, Tolis G, Levi E, Mills LK, Zaret BL. J Am Coll Cardiol. 1993;22:1411–1417. - PubMed

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