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Review
. 2025 Feb 1;26(2):88-101.
doi: 10.2459/JCM.0000000000001694. Epub 2024 Dec 27.

Diagnosis of atrial cardiomyopathy: from the electrocardiogram to the new opportunities with multimodality imaging

Affiliations
Review

Diagnosis of atrial cardiomyopathy: from the electrocardiogram to the new opportunities with multimodality imaging

Martina Belli et al. J Cardiovasc Med (Hagerstown). .

Abstract

Atrial cardiomyopathy (AC) has been defined by the European Heart Rhythm Association as "Any complex of structural, architectural, contractile, or electrophysiologic changes in the atria with the potential to produce clinically relevant manifestations".1 The left atrium (LA) plays a key role in maintaining normal cardiac function; in fact atrial dysfunction has emerged as an essential determinant of outcomes in different clinical scenarios, such as valvular diseases, heart failure (HF), coronary artery disease (CAD) and atrial fibrillation (AF). A comprehensive evaluation, both anatomical and functional, is routinely performed in cardiac imaging laboratories. Recent advances in imaging techniques offer opportunities for evaluation of LA function, fundamental in clinical practice for early cardiovascular (CV) risk estimation, choice of therapeutic intervention and follow up. In this review we explore the concept of AC, its diagnosis through a multimodal approach, ranging from the historical electrocardiogram to the latest CV imaging techniques and its clinical implications.

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References

    1. Goette A, Kalman JM, Aguinaga L, et al. Document reviewers: EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication. Europace 2016; 18:1455–1490.
    1. Seward JB, Hebl VB. Left atrial anatomy and physiology: echo/Doppler assessment. Curr Opin Cardiol 2014; 29:403–407.
    1. Levin ER, Gardner DG, Samson WK. Natriuretic peptides. N Engl J Med 1998; 339:321–328.
    1. Scheuer DA, Thrasher TN, Ramsay DJ. Role of renal sympathetic nerves in renin inhibition by elevated left atrial pressure. Am J Physiol 1989; 256 (2 Pt 2):R413–R420.
    1. Coote JH. A role for the paraventricular nucleus of the hypothalamus in the autonomic control of heart and kidney. Exp Physiol 2005; 90:169–173.

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