Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Mar;27(1):33-39.
doi: 10.7461/jcen.2024.E2024.11.002. Epub 2025 Jan 24.

Comparison of Woven EndoBridge and stent-assisted coiling for treatment of acutely ruptured wide-neck bifurcation aneurysms: Single-center experience

Hossein Ghanaati  1 , Aryoobarzan Rahmatian  2   3 , Amir Torkaman  3 , Mohammad Dashtkoohi  3   4 , Mohammad Amin Dabbagh Ohadi  4
Affiliations

Comparison of Woven EndoBridge and stent-assisted coiling for treatment of acutely ruptured wide-neck bifurcation aneurysms: Single-center experience

Hossein Ghanaati et al. J Cerebrovasc Endovasc Neurosurg. 2025 Mar.

Abstract

Objective: Treating wide-necked bifurcation aneurysms (WNBA) is challenging. Nevertheless, recent progress in endovascular techniques is promising. Woven EndoBridge devices (WEB) have exhibited outcomes comparable to conventional treatments like stent-assisted coiling (SAC) in treating aneurysms. However, their safety and efficacy in managing acutely ruptured aneurysms remain a topic of interest. This study focuses on this issue.

Methods: We searched our database from 2020 to 2023 and found 38 patients with acutely (< a week) ruptured WNBA. We extracted radiologic and clinical data from the available medical reports. Favorable functional and radiologic outcomes were assessed using the modified Rankin scale (mRS) and modified Raymond-Roy occlusion classification (MRRC).

Results: Our study population comprised 15 aneurysms treated with WEB and 25 treated with SAC. Operational time was significantly lower in the WEB compared to the SAC group (39.3 vs 66.2 minutes, p value: < 0.001). Immediate (p value=0.64) and the 18th-month (p value=0.42) occlusion rates were comparable between the two groups. Favorable mRS scores in the 3rd month were seen in 100% of SAC patients and 93.3% of WEB patients (p value=0.79). Retreatment (p value=1.0) and complication (p value=0.39) rates were comparable. Vasospasms after the procedure were the most common complication.

Conclusions: WEB demonstrated comparable safety and efficacy to SAC in patients with acutely ruptured WNBA. Notably, WEB had a shorter procedure duration. Additional studies with extended follow-up periods are necessary for comprehensive evaluation.

Keywords: Endovascular procedures; Intracranial aneurysm; Prostheses and implants.

PubMed Disclaimer

Conflict of interest statement

Disclosure

The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

Figures

Fig. 1.
Fig. 1.
Schematic of study design. EVT, endovascular treatment; WNB, wide-necked bifurcation
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Arthur AS, Molyneux A, Coon AL, Saatci I, Szikora I, Baltacioglu F, et al. The safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide-necked bifurcation aneurysms: Final 12-month results of the pivotal WEB intrasaccular therapy (WEB-IT) study. J Neurointerv Surg. 2019 Sep;11(9):924–30. - PMC - PubMed
    1. Aydin K, Sencer S, Barburoglu M, Berdikhojayev M, Aras Y, Sencer A, et al. Midterm results of T-stent-assisted coiling of wide-necked and complex intracranial bifurcation aneurysms using low-profile stents. J Neurosurg. 2017 Dec;127(6):1288–96. - PubMed
    1. Celik E, Ozpeynirci Y, Liebig T, Schlamann M, Dorn F, Lehnen N, et al. Comparison of angiographic outcomes and complication rates of WEB embolization and coiling for treatment of unruptured basilar tip aneurysms. Sci Rep. 2022 Jun;12(1):10899. - PMC - PubMed
    1. Ding YH, Lewis DA, Kadirvel R, Dai D, Kallmes DF. The Woven EndoBridge:A new aneurysm occlusion device. AJNR Am J Neuroradiol. 2011 Mar;32(3):607–11. - PMC - PubMed
    1. Fiorella D, Arthur AS, Chiacchierini R, Emery E, Molyneux A, Pierot L. How safe and effective are existing treatments for wide-necked bifurcation aneurysms? Literature-based objective performance criteria for safety and effectiveness. J Neurointerv Surg. 2017 Dec;9(12):1197–201. - PubMed