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Case Reports
. 2025 Feb;72(2):101645.
doi: 10.1016/j.redare.2025.101645. Epub 2025 Jan 23.

Cardiopulmonary arrest in liver transplantation surgery: Perioperative beta-blockade implication in the cirrhotic patient

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Case Reports

Cardiopulmonary arrest in liver transplantation surgery: Perioperative beta-blockade implication in the cirrhotic patient

R C Vela Pascual et al. Rev Esp Anestesiol Reanim (Engl Ed). 2025 Feb.

Abstract

Liver transplantation (LT) has an incidence of intraoperative cardiopulmonary arrest (CPA) of around 5%. Patients who experience CPA during this procedure have a reduced survival rate of approximately 50%. Most CPAs occur during the neohepatic phase due to reperfusion syndrome, but this is not always the underlying cause, and a broad differential diagnosis must be performed. We introduce the case of a cirrhotic patient who received beta-blocker therapy in the preoperative period and who experienced intraoperative CPA during LT surgery, which was successfully resolved through advanced cardiopulmonary resuscitation (CPR) maneuvers and specific treatment for beta-blocker toxicity (calcium and glucagon).

Keywords: Asistolia; Asystole; Beta-blockers; Beta-bloqueantes; Glucagon; Glucagón; Liver transplantation; Trasplante hepático.

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Conflict of interest statement

Declaration of competing interest The authors have no conflicts of interest to declare.

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