Advancements in Public First Responder Programs for Out-of-Hospital Cardiac Arrest: An Updated Literature Review
- PMID: 39867188
- PMCID: PMC11760550
- DOI: 10.31083/RCM26140
Advancements in Public First Responder Programs for Out-of-Hospital Cardiac Arrest: An Updated Literature Review
Abstract
Out-of-hospital cardiac arrest (OHCA) is a leading cause of death worldwide, with a low survival rate of around 7% globally. Key factors for improving survival include witnessed arrest, bystander cardiopulmonary resuscitation (CPR), and early defibrillation. Despite guidelines advocating for the "chain of survival", bystander CPR and defibrillation rates remain suboptimal. Innovative approaches, such as dispatcher-assisted CPR (DA-CPR) and smartphone-based alerts, have emerged to address these challenges. DA-CPR effectively transforms emergency callers into lay rescuers, and smartphone apps are increasingly being used to alert volunteer first responders to OHCA incidents, enhancing response times and increasing survival rates. Smartphone-based systems offer advantages over traditional text messaging by providing real-time guidance and automated external defibrillator (AED) locations. Studies show improved outcomes with app-based alerts, including higher rates of early CPR, increased survival rates and improved neurological outcomes. Additionally, the potential of unmanned aerial vehicles (drones) to deliver AEDs rapidly to OHCA sites has been demonstrated, particularly in rural areas with extended emergency medical services response times. Despite technological advancements, challenges such as ensuring responder training, effective dispatching, and maintaining responder well-being, particularly during the coronavirus disease 19 (COVID-19) pandemic, remain. During the pandemic, some community first responder programs were suspended or modified due to shortages of personal protective equipment (PPE) and increased risks of infection. However, systems that adapted by using PPE and revising protocols generally maintained responder participation and effectiveness. Moving forward, integrating new technology within robust responder systems and support mechanisms will be essential to improving OHCA outcomes and sustaining effective response networks.
Keywords: AED; COVID-19; drones; out-of-hospital cardiac arrest; smartphone alert; volunteer first responder.
Copyright: © 2025 The Author(s). Published by IMR Press.
Conflict of interest statement
The authors declare no conflict of interest.
Figures

Similar articles
-
Use of automated external defibrillators in cardiac arrest: an evidence-based analysis.Ont Health Technol Assess Ser. 2005;5(19):1-29. Epub 2005 Dec 1. Ont Health Technol Assess Ser. 2005. PMID: 23074470 Free PMC article.
-
Out-of-hospital cardiac arrest surveillance --- Cardiac Arrest Registry to Enhance Survival (CARES), United States, October 1, 2005--December 31, 2010.MMWR Surveill Summ. 2011 Jul 29;60(8):1-19. MMWR Surveill Summ. 2011. PMID: 21796098
-
Drones delivering automated external defibrillators-Integrating unmanned aerial systems into the chain of survival: A simulation study in rural Germany.Resuscitation. 2022 Mar;172:139-145. doi: 10.1016/j.resuscitation.2021.12.025. Epub 2021 Dec 28. Resuscitation. 2022. PMID: 34971721
-
Drones delivering automated external defibrillators: A new strategy to improve the prognosis of out-of-hospital cardiac arrest.Resuscitation. 2023 Jan;182:109669. doi: 10.1016/j.resuscitation.2022.12.007. Epub 2022 Dec 16. Resuscitation. 2023. PMID: 36535307 Review.
-
Community Interventions for Out-of-Hospital Cardiac Arrest in Resource-Limited Settings: A Scoping Review Across Low, Middle, and High-Income Countries.Prehosp Emerg Care. 2023;27(8):1088-1100. doi: 10.1080/10903127.2023.2231559. Epub 2023 Jul 18. Prehosp Emerg Care. 2023. PMID: 37406163
References
-
- McNally B, Robb R, Mehta M, Vellano K, Valderrama AL, Yoon PW, et al. Out-of-hospital cardiac arrest surveillance - Cardiac Arrest Registry to Enhance Survival (CARES) Surveillance Summaries (Washington, D.C.: 2002) . 2011;60:1–19. - PubMed
Publication types
LinkOut - more resources
Full Text Sources