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Review
. 2025 Jan 22;26(1):26140.
doi: 10.31083/RCM26140. eCollection 2025 Jan.

Advancements in Public First Responder Programs for Out-of-Hospital Cardiac Arrest: An Updated Literature Review

Affiliations
Review

Advancements in Public First Responder Programs for Out-of-Hospital Cardiac Arrest: An Updated Literature Review

Michael Kern et al. Rev Cardiovasc Med. .

Abstract

Out-of-hospital cardiac arrest (OHCA) is a leading cause of death worldwide, with a low survival rate of around 7% globally. Key factors for improving survival include witnessed arrest, bystander cardiopulmonary resuscitation (CPR), and early defibrillation. Despite guidelines advocating for the "chain of survival", bystander CPR and defibrillation rates remain suboptimal. Innovative approaches, such as dispatcher-assisted CPR (DA-CPR) and smartphone-based alerts, have emerged to address these challenges. DA-CPR effectively transforms emergency callers into lay rescuers, and smartphone apps are increasingly being used to alert volunteer first responders to OHCA incidents, enhancing response times and increasing survival rates. Smartphone-based systems offer advantages over traditional text messaging by providing real-time guidance and automated external defibrillator (AED) locations. Studies show improved outcomes with app-based alerts, including higher rates of early CPR, increased survival rates and improved neurological outcomes. Additionally, the potential of unmanned aerial vehicles (drones) to deliver AEDs rapidly to OHCA sites has been demonstrated, particularly in rural areas with extended emergency medical services response times. Despite technological advancements, challenges such as ensuring responder training, effective dispatching, and maintaining responder well-being, particularly during the coronavirus disease 19 (COVID-19) pandemic, remain. During the pandemic, some community first responder programs were suspended or modified due to shortages of personal protective equipment (PPE) and increased risks of infection. However, systems that adapted by using PPE and revising protocols generally maintained responder participation and effectiveness. Moving forward, integrating new technology within robust responder systems and support mechanisms will be essential to improving OHCA outcomes and sustaining effective response networks.

Keywords: AED; COVID-19; drones; out-of-hospital cardiac arrest; smartphone alert; volunteer first responder.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Incorporating automated external defibrillator (AED) delivery by drone into the chain of survival. After a 911 call for a suspected out-of-hospital cardiac arrest (OHCA), the dispatch center alerts emergency medical service (EMS) and volunteer first responder (VFR) while providing dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) to the caller. Simultaneously, a drone carrying an AED is dispatched to the OHCA site, delivering the AED for use by VFR. The location of the victim and the AED delivery site are displayed on the smartphone app used by the VFR.

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