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. 2025 Feb;21(2):e14485.
doi: 10.1002/alz.14485. Epub 2025 Jan 27.

Prevalence of dementia in Singapore: Changes across a decade

Mythily Subramaniam  1   2   3 , Edimansyah Abdin  1 , P V Asharani  1 , Kumarasan Roystonn  1 , Fiona Devi  1 , Wang Peizhi  1 , Saleha Shafie  1 , Vathsala Sagayadevan  1 , Anitha Jeyagurunathan  1 , Boon Yiang Chua  1 , Bernard Tan  1 , Janhavi Ajit Vaingankar  1 , Fengyuan Yao  4 , Harish Magadi  4 , Stefan Ma  5 , Wai Leng Chow  5 , Paul McCrone  6 , Derrick Heng  5 , Rathi Mahendran  7 , Martin Prince  8 , Li Ling Ng  9 , Siow Ann Chong  1
Affiliations

Prevalence of dementia in Singapore: Changes across a decade

Mythily Subramaniam et al. Alzheimers Dement. 2025 Feb.

Abstract

Introduction: The study aimed to assess changes in the prevalence of dementia in Singapore over the past decade.

Methods: The Well-being of the Singapore Elderly (WiSE) 2023 and the WiSE 2013 studies were comprehensive, single-phase, cross-sectional surveys conducted among older adults aged ≥60 years in Singapore. WiSE 2023 included 2010 older adults and 1798 informants, whereas WiSE 2013 comprised 2565 older adults and 2421 informants.

Results: The weighted prevalence of dementia based on the 10/66 Diagnostic Research Group (DRG) criteria was 8.8% (95% confidence interval [CI]: 7.3-10.7) in the WiSE 2023 study compared to 10% in the WiSE 2013 study (95% CI: 8.7-11.5). The proportion of those with undiagnosed dementia decreased significantly from 70.6% in WiSE 2013 to 51.5% in WiSE 2023 (p-value = 0.002).

Discussion: A non-significant 12% reduction (95% CI: 1.1-3.5) in dementia prevalence was observed in Singapore over a decade, based on the WiSE 2013 and WiSE 2023 studies.

Highlights: The prevalence of dementia decreased from 10% to 8.8% over a decade in Singapore. The prevalence varied by age group, ethnicity, employment status, and health factors. The prevalence of undiagnosed dementia decreased significantly from 70.6% to 51.5%.

Keywords: 10/66 protocol; Asian; dementia; epidemiology; multi‐ethnic.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Prevalence of dementia by severity.
See this image and copyright information in PMC

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