Exposure profiles, determinants, and health risks of chemicals in personal care products among healthy older adults from the China BAPE study

Xiaojie Guo¹, Jiankun Qian², Huimin Ren², Enmin Ding³, Xiao Ma⁴, Jiran Zhang², Tian Qiu⁵, Yifu Lu⁵, Peijie Sun⁶, Chenfeng Li⁴, Chenlong Li⁴, Yibo Xu², Kangning Cao⁷, Xiao Lin⁵, Chen Mao⁸, Shilu Tong⁹, Song Tang¹⁰, Xiaoming Shi¹¹

Affiliations

¹ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
² China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, China Medical University, Shenyang, Liaoning, China.
³ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
⁴ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Shandong University, Jinan, Shandong, China.
⁵ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
⁶ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
⁷ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Anhui Medical University, Hefei, Anhui, China.
⁸ School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
⁹ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.
¹⁰ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address: tangsong@nieh.chinacdc.cn.
¹¹ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address: shixm@chinacdc.cn.

PMID: 39869979
DOI: 10.1016/j.jhazmat.2025.137365

Exposure profiles, determinants, and health risks of chemicals in personal care products among healthy older adults from the China BAPE study

Xiaojie Guo et al. J Hazard Mater. 2025.

. 2025 May 5:488:137365.

doi: 10.1016/j.jhazmat.2025.137365. Epub 2025 Jan 25.

Authors

Affiliations

¹ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
² China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, China Medical University, Shenyang, Liaoning, China.
³ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
⁴ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Shandong University, Jinan, Shandong, China.
⁵ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
⁶ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
⁷ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health, Anhui Medical University, Hefei, Anhui, China.
⁸ School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
⁹ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.
¹⁰ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address: tangsong@nieh.chinacdc.cn.
¹¹ China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address: shixm@chinacdc.cn.

PMID: 39869979
DOI: 10.1016/j.jhazmat.2025.137365

Abstract

Personal care products (PCPs) are ubiquitously present in the environment, and the associated health risks have been increasingly concerned worldwide. However, knowledge regarding exposure assessments of older adults to these chemicals and their health risks remains largely limited. In the present study, five repeated surveys involving 76 healthy older adults in Jinan, Shandong Province, were performed to quantify urinary exposure levels of 14 chemicals in PCPs. Moreover, influencing factors and health risks associated with exposure to these chemicals were thoroughly analyzed. Our findings revealed that methyl paraben (MeP) was the predominant chemical in PCP in the urine of the elderly, with a median concentration of 16.17 μg/L. Dietary intake, particularly fish and milk products, along with exposure to ambient PM_2.5, were identified as the primary sources of certain chemicals in PCPs. Additionally, an increased physical activity was associated with decreased concentrations of benzophenone-2 (BP-2) within the body. Risk assessment demonstrated that chemicals in PCPs currently posed minimal health risks to the elderly. Our findings provide substantial references for mitigating the health risks of these chemical exposures in healthy older adults, ultimately safeguarding their overall and physical well-being.

Keywords: Healthy older adults; Influencing factors; Personal care products; Risk assessments.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Exposure profiles, determinants, and health risks of chemicals in personal care products among healthy older adults from the China BAPE study

Affiliations

Exposure profiles, determinants, and health risks of chemicals in personal care products among healthy older adults from the China BAPE study

Authors

Affiliations

Abstract

Conflict of interest statement

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Medical