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. 2022 Jun 28;1(2):81-83.
doi: 10.1093/lifemedi/lnac016. eCollection 2022 Oct.

Failures at every level: breakdown of the epigenetic machinery of aging

Dongxin Zhao  1 , Song Chen  2
Affiliations

Failures at every level: breakdown of the epigenetic machinery of aging

Dongxin Zhao et al. Life Med. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1.
Figure 1.
Schematic overview of spatial genome architectures in growing (center) and senescent (gray boxes) stem cells. Senescence is accompanied by erosion of chromatin organization across multiple hierarchic layers, which exhibits convergent epigenetic patterns due to the weakened repressive (shown in blue) and active (shown in red) chromatin states. NL, nuclear lamina.
See this image and copyright information in PMC

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