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. 2025 Jan 27;17(1):101326.
doi: 10.4240/wjgs.v17.i1.101326.

Perioperative chemotherapy strategies in diffuse gastric cancer

Niloufar Salehi  1 , Maria Alqamish  1 , Rasa Zarnegar  2
Affiliations

Perioperative chemotherapy strategies in diffuse gastric cancer

Niloufar Salehi et al. World J Gastrointest Surg. .

Abstract

This study reviews the findings of a recent study by Li et al, which demonstrated that perioperative chemotherapy benefits patients with diffuse-type gastric cancer compared to surgery alone. Despite potential biases, the study supports the inclusion of perioperative chemotherapy in treatment guidelines. Neoadjuvant and adjuvant chemotherapy may also provide similar survival outcomes, allowing for flexible treatment planning.

Keywords: Adjuvant chemotherapy; Gastric adenocarcinoma; Gastric cancer; Neoadjuvant chemotherapy; Survival.

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Conflict of interest statement

Conflict-of-interest statement: Dr. Rasa Zarnegar works as a consultant for Intuitive, Medtronic, and Beckton-Dickenson. Drs. Niloufar Salehi and Maria Alqamish have no conflicts of interest or financial ties to disclose.

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