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. 2025 Jan 28;1(1):CD014212.
doi: 10.1002/14651858.CD014212.

Dexmedetomidine for analgesia and sedation for procedural pain or discomfort in newborn infants

Affiliations

Dexmedetomidine for analgesia and sedation for procedural pain or discomfort in newborn infants

Nai Ming Lai et al. Cochrane Database Syst Rev. .

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of dexmedetomidine compared with opioids, non-opioids and placebo in providing sedation and analgesia for procedural pain in newborn infants.

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Conflict of interest statement

Nai Ming Lai is an Associate Editor for Cochrane Neonatal, and a Sign‐off Editor for Cochrane Central Editorial Service. However, he did not participate in the editorial process for this protocol.

Michelle Fiander is a Managing Editor and Information Specialist for Cochrane Neonatal; however, she did not participate in the editorial process for this protocol.

Jane Cracknell is a Managing Editor for Cochrane Neonatal; however, she did not participate in the editorial process for this protocol.

Kenneth Tan has no conflicts of interest to declare.

Olga Romantsik has no conflicts of interest to declare.

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References

    1. Anand KJ, Aranda JV, Berde CB, Buckman S, Capparelli EV, Carlo W, et al. Summary proceedings from the neonatal pain-control group. Pediatrics 2006;117(3 Pt 2):S9-22. [DOI: 10.1542/peds.2005-0620C] [PMID: ] - DOI - PubMed
    1. Carbajal R, Rousset A, Danan C, Coquery S, Nolent P, Ducrocq S, et al. Epidemiology and treatment of painful procedures in neonates in intensive care units. JAMA 2008;300(1):60-70. [DOI: 10.1001/jama.300.1.60] [PMID: ] - DOI - PubMed
    1. Anand KJ. Clinical importance of pain and stress in preterm neonates. Biology of the Neonate 1998;73(1):1-9. [DOI: 10.1159/000013953] [PMID: ] - DOI - PubMed
    1. Fitzgerald M. The development of nociceptive circuits. Nature Reviews Neuroscience 2005;6(7):507-20. [DOI: 10.1038/nrn1701] [PMID: ] - DOI - PubMed
    1. Marchant A. 'Neonates do not feel pain': a critical review of the evidence. Bioscience Horizons: The International Journal of Student Research 2014;7:hzu006. [DOI: 10.1093/biohorizons/hzu006] - DOI

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