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Observational Study
. 2025 Jan 29;45(1):43.
doi: 10.1007/s10792-025-03406-8.

Drainage from intentional extramacular holes after internal limiting membrane insertion to treat macular hole retinal detachment in highly myopic eyes

Zhijian Huang  1 , Qin Ding  1 , Xiao Chen  2   3 , Li Zhu  1 , Ying Yan  1 , Miao Zeng  1 , Cheng Hu  1 , Nian Xiang  1
Affiliations
Observational Study

Drainage from intentional extramacular holes after internal limiting membrane insertion to treat macular hole retinal detachment in highly myopic eyes

Zhijian Huang et al. Int Ophthalmol. .

Abstract

Purpose: The purpose is to evaluate the effect of drainage from intentional extramacular holes after internal limiting membrane insertion to treat macular hole retinal detachment (MHRD) in highly myopic eyes.

Methods: This study is a retrospective, observational, and comparative case series that included 25 consecutive highly myopic eyes with MHRD. All eyes underwent standard 23-gauge vitrectomy, inverted internal limiting membrane insertion into the macular hole, subretinal fluid drainage from an intentionally created extramacular retinal hole, and tamponade with either silicone oil (SO group, n = 13) or perfluoropropane (C3F8 group, n = 12). A facedown position was maintained for 1 week postoperatively. The anatomic and functional outcomes were compared between two groups at the endpoint.

Results: There was no significant difference in the retinal reattachment rate between the SO and C3F8 groups (100% and 91.67%, P = 0.48). The macular hole closure rates were 92.31% in the SO group and 100% in the C3F8 group (P = 0.52). The mean best-corrected visual acuity (BCVA) improved from 2.18 ± 0.60 logarithm of the minimum angle of resolution(logMAR) preoperatively to 1.11 ± 0.36 logMAR (P < 0.01) in the SO group and from 2.20 ± 0.61 to 1.29 ± 0.50 (P < 0.01) in the C3F8 group at the endpoint. There was no significant difference in BCVA improvement between the two groups (P = 0.37).

Conclusion: The drainage technique from intentional extramacular holes after internal limiting membrane insertion is an effective treatment for MHRD in highly myopic eyes, regardless of whether silicone oil or gas is used as a tamponade.

Keywords: High myopia; Intentional extramacular hole; Internal limiting membrane insertion; Macular hole retinal detachment.

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Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests.

References

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