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Review
. 2025 Jan 2;25(1):10-16.
doi: 10.4103/tjem.tjem_129_24. eCollection 2025 Jan-Mar.

Mushroom poisoning: An updated review

Affiliations
Review

Mushroom poisoning: An updated review

Mustafa Oğuz Tuğcan et al. Turk J Emerg Med. .

Abstract

Mushrooms have been consumed frequently worldwide since ancient times. In addition to edible and harmless species, there are also poisonous species that cause a wide range of clinical syndromes, from simple gastrointestinal (GI) irritation to death. However, it is not possible to distinguish the poisonous species from some edible species morphologically. Therefore, the unintentional consumption of mushrooms is an important public health problem. Mushrooms can be categorized according to their toxins, such as cyclopeptides, gyromitrin, muscarine, coprine, orellanine, psilocybin, and GI irritants. Mushrooms containing cyclopeptide-amatoxin are responsible for more than 90% of deaths due to mushroom poisoning. Amanita phalloides is responsible for many fatal cases because of the toxicity of this species. This article reviews the clinical syndromes that may develop after the consumption of various poisonous mushroom species, the mechanisms of action of their toxins, and the current treatments applied.

Keywords: Acute renal failure; liver injury; mushroom poisoning; mushroom species; toxicity.

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Conflict of interest statement

None Declared.

References

    1. Sandargo B, Chepkirui C, Cheng T, Chaverra-Muñoz L, Thongbai B, Stadler M, et al. Biological and chemical diversity go hand in hand: Basidiomycota as source of new pharmaceuticals and agrochemicals. Biotechnol Adv. 2019;37:107344. - PubMed
    1. Diaz JH. Amatoxin-containing mushroom poisonings: Species, toxidromes, treatments, and outcomes. Wilderness Environ Med. 2018;29:111–8. - PubMed
    1. Yin X, Yang AA, Gao JM. Mushroom toxins: Chemistry and toxicology. J Agric Food Chem. 2019;67:5053–71. - PubMed
    1. Eren SH, Demirel Y, Ugurlu S, Korkmaz I, Aktas C, Güven FM. Mushroom poisoning: Retrospective analysis of 294 cases. Clinics (Sao Paulo) 2010;65:491–6. - PMC - PubMed
    1. Kaya E, Yilmaz I, Sinirlioglu ZA, Karahan S, Bayram R, Yaykasli KO, et al. Amanitin and phallotoxin concentration in Amanita phalloides var. Alba mushroom. Toxicon. 2013;76:225–33. - PubMed

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