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Case Reports
. 2024 Jul-Dec;45(2):125-128.
doi: 10.4103/ijstd.ijstd_5_24. Epub 2024 Dec 13.

Unusual manifestations of syphilis in HIV

Sameeha Hamza Chenganasseri  1 , Suraj Mali  1 , Amulya Bathula  1 , Indira Danturty  1 , A Venkata Krishna  1 , T Rajeev Singh  1
Affiliations
Case Reports

Unusual manifestations of syphilis in HIV

Sameeha Hamza Chenganasseri et al. Indian J Sex Transm Dis AIDS. 2024 Jul-Dec.

Abstract

Over the past decade, there has been a significant increase in cases with syphilis and HIV coinfection. Concordant infection with HIV can alter the clinical course and response to treatment in syphilis. Variable and unusual presentations of syphilis in HIV disease can make early diagnosis and treatment challenging. We, herein, report four cases of atypical manifestations of syphilis in patients with HIV coinfection.

Keywords: Coinfection; HIV infection; secondary syphilis.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Papule with rupioid crusting over the lower limb
Figure 2
Figure 2
Papule with rupioid crusting over the trunk
Figure 3
Figure 3
Dermis showed obliteration of vascular lumina with infiltration of plasma cells (magnification 40 X)
Figure 4
Figure 4
Concentric, circinate, scaly plaques over the feet
Figure 5
Figure 5
Dense collection of lymphoplasmacytic cells seen in the superficial dermis (magnification-40 X)
Figure 6
Figure 6
Hyperpigmented crusted plaques over the back, distributed symmetrically
Figure 7
Figure 7
Multiple crusted nodules over the glans penis
Figure 8
Figure 8
Multiple, scaly, erythematous papules and plaques over the nose, chin, cheeks, and forehead
Figure 9
Figure 9
Multiple noncaseating granulomas with epithelioid cells, lymphocytes, plasma cells, histiocytes, and plasma cells (magnification-4 X)
See this image and copyright information in PMC

References

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