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Case Reports
. 2024 Dec 31;16(12):e76675.
doi: 10.7759/cureus.76675. eCollection 2024 Dec.

A 21-Year-Old Male With Metastatic Colorectal Cancer: A Case Report and Literature Overview of Early-Onset Colorectal Cancer

Daniel Aintabi  1 , Stephanie Mackenzie  1 , Wael Al-Yaman  2 , Kevin Wenzke  3 , Jeffrey Berinstein  4
Affiliations
Case Reports

A 21-Year-Old Male With Metastatic Colorectal Cancer: A Case Report and Literature Overview of Early-Onset Colorectal Cancer

Daniel Aintabi et al. Cureus. .

Abstract

Early-onset colorectal cancer (CRC) has been on the rise since the start of the twenty-first century. While the etiology behind this increase remains unclear, the United States Preventive Services Task Force (USPSTF) has decreased the recommended age to begin screening for CRC to 45 years. This case report reviews the literature on CRC in the young population while presenting a case of a 21-year-old male with early-onset metastatic colorectal cancer without a hereditary etiology.

Keywords: chemotherapy for advanced colorectal cancer; colorectal cancer; colorectal cancer liver metastases; metastatic colorectal cancer (mcrc); young onset colorectal cancer.

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Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: Jeffrey Berinstein declare(s) personal fees from OSHI Health and Teka. Consulting fees. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. CT abdomen and pelvis (AP) demonstrating the largest liver metastasis, measuring 6.4 cm.
Figure 2
Figure 2. MR abdomen showing the largest hepatic metastasis.
Figure 3
Figure 3. CT abdomen and pelvis (AP) with rectal contrast demonstrating two colonic apple core lesions measuring 1.7 cm and 1.0 cm.
Figure 4
Figure 4. Colonoscopy with ulcerated nonobstructing mass in sigmoid colon.
Figure 5
Figure 5. CT after 10 months of chemotherapy and immunotherapy with decreased size of hepatic metastases with the largest measuring 2.9 cm.
See this image and copyright information in PMC

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