Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2025 Apr;21(2):e13809.
doi: 10.1111/mcn.13809. Epub 2025 Jan 31.

Piloting Multiple Micronutrient Supplementation Within the Routine Antenatal Care System in Ethiopia: Insights From Stakeholders

Affiliations
Randomized Controlled Trial

Piloting Multiple Micronutrient Supplementation Within the Routine Antenatal Care System in Ethiopia: Insights From Stakeholders

Anene Tesfa Berhanu et al. Matern Child Nutr. 2025 Apr.

Abstract

In low and middle-income countries, addressing maternal and child nutrition needs is crucial. Prenatal multiple micronutrient supplementation (MMS) holds promise in reducing low birthweight and preterm births. Ethiopia is considering a transition from the provision of iron-folate supplementation to the provision of MMS in antenatal care, guided by WHO guidelines. This paper explores stakeholders' early perceptions and experiences in piloting that transition in five Ethiopian regions, informing decision making about future policy and scale-up. We used a qualitative study involving interviews and document reviews to assess the MMS pilot, analyzing themes with Nvivo 12 software. Key informant interviews revealed challenges such as supply chain issues and funding constraints, along with proposed improvement strategies such as closer coordination within existing structures. The importance of engaging with communities to create demand was emphasized, as was the need for capacity-building efforts utilizing existing staff in the health system with a clear plan for ongoing refresher training. Finally, enhancing the monitoring and evaluation framework, including a dedicated regional team for supportive supervision, was vital for accountability. In conclusion, prioritizing supply chain strengthening, community engagement through demand creation, coordination, and continuous capacity building for healthcare workers were thought to be crucial for the MMS program's success. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT05708183 Registered 01 February 2023-Retrospectively registered, https://classic.clinicaltrials.gov/ct2/show/NCT05708183.

Keywords: antenatal care; capacity‐building; child nutrition; maternal nutrition; micronutrient deficiencies; program implementation; stakeholder perceptions.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Similar articles

Cited by

References

    1. Abdelrahman, W. , and Abdelmageed A.. 2014. “Medical Record Keeping: Clarity, Accuracy, and Timeliness Are Essential.” BMJ 348: f7716. https://www.bmj.com/content/348/bmj.f7716.
    1. Ahmed, F. , Khan M. R., Akhtaruzzaman M., et al. 2005. “Efficacy of Twice‐Weekly Multiple Micronutrient Supplementation for Improving the Hemoglobin and Micronutrient Status of Anemic Adolescent Schoolgirls in Bangladesh.” American Journal of Clinical Nutrition 82, no. 4: 829–835. 10.1093/ajcn/82.4.829. - DOI - PubMed
    1. Caniglia, E. C. , Zash R., Swanson S. A., et al. 2022. “Iron, Folic Acid, and Multiple Micronutrient Supplementation Strategies During Pregnancy and Adverse Birth Outcomes in Botswana.” Lancet Global Health 10: e850–e861. 10.1016/S2214-109X(22)00126-7. - DOI - PMC - PubMed
    1. Central Statistical Agency (CSA) [Ethiopia] and ICF . 2022. Ethiopia Demographic and Health Survey 2022: Key Indicators Report. CSA and ICF.
    1. Fuentes‐Afflick, E. , Perrin J. M., Moley K. H., Díaz Á., McCormick M. C., and Lu M. C.. 2021. “Optimizing Health and Well‐Being for Women and Children.” Health Affairs 40, no. 2: 212–218. 10.1377/hlthaff.2020.01504. - DOI - PubMed

Publication types

Associated data