Vaccines and Other Preventative Strategies for Immunocompromised Pneumonia

Abstract

Immunocompromised patients are more susceptible to infections. Although they have reduced immune response to vaccines, it is still essential to prioritize immunizations as one strategy to potentially reduce the impact of pneumonia in this vulnerable population. Response to immunizations in immunocompromised patients can be enhanced by increasing the dose of vaccines (eg, influenza) or by increasing the number of doses (eg, coronavirus disease 2019). Prophylactic use of antimicrobials, control of risk factors (avoidance of smoking), and stabilization of underlying conditions (eg, chronic obstructive pulmonary disease) can also have a beneficial effect to reduce the likelihood of pneumonia in the immunocompromised host.

Keywords: Immunization; Immunocompromise; Immunosuppression; Pneumonia; Prevention; Prophylaxis; Vaccine.