Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Feb 1;317(1):337.
doi: 10.1007/s00403-025-03835-6.

Demographic and clinicopathological features of cutaneous vasculitis

Milad Gandomi-Mohammadabadi  1 , Alireza Gandomi-Mohammadabadi  2 , Maryam Nasimi  1   3 , Ifa Etesami  1   3 , Hamidreza Mahmoudi  1   3 , Zeinab Aryanian  4   5   6 , Parvaneh Hatami  7
Affiliations

Demographic and clinicopathological features of cutaneous vasculitis

Milad Gandomi-Mohammadabadi et al. Arch Dermatol Res. .

Abstract

Background & objective: Cutaneous vasculitis has different clinical manifestations. It may be idiopathic or associated with infections, medications, etc.Skin is involved in both small vessel vasculitis (SVV) and medium vascular vasculitis.We aimed to evaluate clinical signs, laboratory and pathological changes of cutaneous vasculitis among Iranian people.

Material & methods: This study was a descriptive study performed on 74 patients with cutaneous vasculitis from March 2011 to February 2019. Information includes histopathological data, as well as clinical variables including the age of onset, sex, area of involvement, type of lesion, symptoms, and diagnosis. Pathological and laboratory changes were collected and recorded as well.

Results: Of the 74 patients studied, hypersensitivity vasculitis 52(70%) was the most common form.Most of the patients had lower extremities involvement. The most common clinical features and symptoms were petechiae or purpura and itching. Fever, limb edema, and arthralgia were the most common symptoms, occurring in 26%, 20%, and 18% of patients, respectively. Among patients, 18 (24%) had taken medication before the lesions, 10 (13%) had vasculitis due to infection, and 44 (59%) were diagnosed as idiopathic form. The most common treatment was prednisolone in 69 patients (93%) with a mean dose of 15.6 ± 35 mg.

Conclusion: The study would be useful in understanding the various specific and non specific features of cutaneous vasculitis, helping the clinician to manage the condition.

Keywords: Cutaneous vasculitis; Hypersensitivity vasculitis; Inflammatory factors; Vasculitis.

PubMed Disclaimer

Conflict of interest statement

Declarations. Ethics approval: Ethical approval from the Medical Ethics Committee of Tehran University of Medical Sciences was provided. Conflict of interest: The authors declare that they have no competing interests.

Similar articles

See all similar articles

References

    1. Pulido-Pérez A, Avilés-Izquierdo JA, Suárez-Fernández R (2012) [Cutaneous vasculitis]. Actas dermo-sifiliograficas 103(3):179–191 - DOI - PubMed
    1. Tai YJ, Chong AH, Williams RA, Cumming S, Kelly RI (2006) Retrospective analysis of adult patients with cutaneous leukocytoclastic vasculitis. Australas J Dermatol 47(2):92–96 - DOI - PubMed
    1. Alberti-Violetti S, Berti E, Marzano AV (2018) Cutaneous and systemic vasculitides in dermatology: a histological perspective. G Ital Dermatol Venereol 153(2):185–193 - PubMed
    1. Amirhoushang E, Hossein M, Arghavan A, Mahsa A, Edris T, Azadeh G, Ziba R, Zeinab A (2014) Basic data of patients with skin drug reactions admitted to Razi Hospital, Tehran, Iran. Iran J Dermatology 17(2):63–67
    1. Carlson JA (2010) The histological assessment of cutaneous vasculitis. Histopathology 56(1):3–23 - DOI - PubMed

MeSH terms

LinkOut - more resources