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Review
. 2025 Feb 26;73(8):4440-4454.
doi: 10.1021/acs.jafc.4c10736. Epub 2025 Feb 2.

The Whey-Plant Protein Heteroprotein Systems with Synergistic Properties and Versatile Applications

Affiliations
Review

The Whey-Plant Protein Heteroprotein Systems with Synergistic Properties and Versatile Applications

Chang Liu et al. J Agric Food Chem. .

Abstract

Combining animal protein with plant protein is a feasible approach to provide heteroprotein formulations with versatile properties. This review introduces the interactions of typical protein whey protein (WP) from milk with soy protein (SP), pea protein (PP), rapeseed protein (RAP), lupine protein (LP), and rice protein (RIP) through physical and chemical methods. The characteristics of whey-plant protein complexes are described with particular emphasis on the protein types, structures, and properties. In addition, the factors that influence the formation of whey-plant complexes are reviewed. The potential food applications of whey-plant protein complexes are reviewed. Overcoming the shortcomings and future challenges for applications of the heteroprotein in the food field are highlighted. This review will fill the gap of whey protein and are important for the development of more versatile properties of whey proteins as well as a systematic understanding of the synergistic biological roles of these active proteins.

Keywords: Challenge; Heteroprotein; Plant protein; Structure; Whey protein.

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