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. 2025 Mar;178(3):e2403549.
doi: 10.7326/ANNALS-24-03549. Epub 2025 Feb 4.

Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians (Version 1, Update Alert 2, Surveillance Note 1)

Amir Qaseem  1 , Douglas K Owens  2 , Itziar Etxeandia-Ikobaltzeta  1 , J Thomas Cross Jr  3 , Jennifer Yost  4 , Carolyn J Crandall  5 ; Clinical Guidelines Committee of the American College of Physicians; Carolyn J Crandall, Lauri A Hicks, Ethan M Balk, Thomas G Cooney, J Thomas Cross Jr, Nick Fitterman, Johanna Lewis, Amy M Linsky, Michael Maroto, Matthew C Miller, Adam J Obley, Douglas K Owens, Paul G Shekelle, Jeffrey A Tice, Itziar Etxeandia-Ikobaltzeta, Curtis S Harrod, Amir Qaseem, Jennifer Yost
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Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians (Version 1, Update Alert 2, Surveillance Note 1)

Amir Qaseem et al. Ann Intern Med. 2025 Mar.
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Conflict of interest statement

Disclosures: All financial and intellectual disclosures of interest were declared, and potential conflicts were discussed and managed. No committee members were recused from participation due to a conflict of interest. A record of disclosures of interest and management of conflicts is kept for each Clinical Guidelines Committee meeting and conference call and can be viewed at www.acponline.org/clinical_information/guidelines/guidelines/conflicts_cgc.htm. Disclosure forms are available with the article online.

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