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. 2025 Feb;24(1):59-61.
doi: 10.1007/s12663-024-02218-0. Epub 2024 Jun 11.

Pyoderma Gangrenosum with Oral Involvement and Multidisciplinary Management

Héric de Souza Camargo  1 , Carolina da Silva Nunes  1 , Claudia Maria Navarro  1 , Elaine Maria Sgavioli Massucato  1 , Marisa Aparecida Cabrini Gabrielli  1 , Valfrido Antonio Pereira Filho  1 , Andreia Bufalino  1
Affiliations

Pyoderma Gangrenosum with Oral Involvement and Multidisciplinary Management

Héric de Souza Camargo et al. J Maxillofac Oral Surg. 2025 Feb.

Abstract

Introduction: Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis often associated with inflammatory bowel disease.

Case report: We present a case of PG affecting the oral mucosa in a 31-year-old female with ulcerative colitis, necessitating total colectomy due to aggressive lesion progression. Despite initial adalimumab treatment, the lesions persisted, prompting a multidisciplinary approach. Following surgical intervention, including total colectomy and microvascularized graft with a forearm flap, the patient remained recurrence-free during a seven-year follow-up.

Conclusion: This case underscores the complexity of PG and highlights the efficacy of a comprehensive therapeutic approach, emphasizing the importance of individualized management strategies in severe cases.

Keywords: Inflammatory bowel disease; Pioderma gangrenosum; Total colectomy.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

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