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Review
. 2025 Mar 20:137:111281.
doi: 10.1016/j.pnpbp.2025.111281. Epub 2025 Feb 2.

Alcohol outcomes on anxiety, impulsivity and spatial memory: Possible Omega-3 amelioration effects

Affiliations
Review

Alcohol outcomes on anxiety, impulsivity and spatial memory: Possible Omega-3 amelioration effects

Valentín Cabrera et al. Prog Neuropsychopharmacol Biol Psychiatry. .

Abstract

Alcohol consumption is a worldwide concern that causes 5 % of the global disease burden and contributes to 3 million deaths per year. Several studies suggest an increase in alcohol drinking and alcohol related problems. Alcohol Use Disorder (formerly referred as alcoholism or alcohol addiction) is one of many possible outcomes of an early and prolonged alcohol consumption and it is highly comorbid with anxiety disorders, impulsivity and memory deficits among others. In this review we approach recent data about global and American prevalence of alcohol use and discuss different factors that contribute to alcohol consumption. Furthermore, we revise evidence of ethanol effects on anxiety-like behaviors, impulsivity and spatial memory. Lastly, we look at the Omega-3 fatty acid as a possible course of action in mitigating the aforementioned deleterious effects of alcohol consumption.

Keywords: Alcohol; Anxiety; Fatty acids; Impulsivity; Omega-3; Spatial memory.

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Conflict of interest statement

Declaration of competing interest Authors Cabrera, Abate, Balaszczuk and Macchione have no conflict of interest to declare.

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