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. 1985 May;315(6014):37-40.
doi: 10.1038/315037a0.

Three-dimensional structure of calmodulin

Y S Babu, J S Sack, T J Greenhough, C E Bugg, A R Means, W J Cook

Three-dimensional structure of calmodulin

Y S Babu et al. Nature. 1985 May.

Abstract

The three-dimensional structure of calmodulin has been determined crystallographically at 3.0 A resolution. The molecule consists of two globular lobes connected by a long exposed alpha-helix. Each lobe binds two calcium ions through helix-loop-helix domains similar to those of other calcium-binding proteins. The long helix between the lobes may be involved in interactions of calmodulin with drugs and various proteins.

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