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. 2025 Oct 1;110(10):2475-2480.
doi: 10.3324/haematol.2024.286807. Epub 2025 Feb 6.

Dexamethasone added to induction and post-remission therapy in older patients with newly diagnosed acute myeloid leukemia: a multicenter, phase II trial (DEXAML-02)

Affiliations

Dexamethasone added to induction and post-remission therapy in older patients with newly diagnosed acute myeloid leukemia: a multicenter, phase II trial (DEXAML-02)

Sarah Bertoli et al. Haematologica. .
No abstract available

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Figures

Figure 1.
Figure 1.
Event-free survival, relapse-free survival and overall survival. (A) Event-free survival in the whole population. (B) Event-free survival according to the 2022 European LeukemiaNet (ELN) classification. (C) Relapse-free survival in the whole population. (D) Relapse-free survival according to the 2022 ELN classification. (E) Overall survival in the whole population. (F) Overall survival according to the 2022 ELN classification. N: number.

References

    1. Döhner H, Wei AH, Appelbaum FR, et al. Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN. Blood. 2022;140(12):1345-1377. - PubMed
    1. Castaigne S, Pautas C, Terré C, et al. Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study. Lancet. 2012;379(9825):1508-1516. - PubMed
    1. Lancet JE, Uy GL, Newell LF, et al. CPX-351 versus 7+3 cytarabine and daunorubicin chemotherapy in older adults with newly diagnosed high-risk or secondary acute myeloid leukaemia: 5-year results of a randomised, open-label, multicentre, phase 3 trial. Lancet Haematol. 2021;8(7):e481-e491. - PubMed
    1. Pigneux A, Béné MC, Salmi LR, et al. Improved survival by adding lomustine to conventional chemotherapy for elderly patients with AML without unfavorable cytogenetics: results of the LAM-SA 2007 FILO trial. J Clin Oncol. 2018;36(32):3203-3210. - PubMed
    1. Bertoli S, Picard M, Bérard E, et al. Dexamethasone in hyperleukocytic acute myeloid leukemia. Haematologica. 2018;103(6):988-998. - PMC - PubMed

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