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. 2025 Mar;206(3):1004-1006.
doi: 10.1111/bjh.20004. Epub 2025 Feb 6.

Use of the IgG degrader imlifidase for a poorly desensitized patient undergoing haematopoietic stem cell transplantation with donor-specific antibodies

Dennis L Cooper  1 , Jhannine Alyssa Verceles  1 , Taba Kheradmand  2 , Monika Paroder  3 , Amanda Lombardo  1 , Mendel Goldfinger  1 , Nishi Shah  1 , Noah Kornblum  1 , Lauren C Shapiro  1 , Marina Konopleva  1 , Aditi Shastri  1 , Ioannis Mantzaris  1 , Roberto A Sica  1 , Kira Gritsman  1 , Eric J Feldman  1 , Amit Verma  1
Affiliations

Use of the IgG degrader imlifidase for a poorly desensitized patient undergoing haematopoietic stem cell transplantation with donor-specific antibodies

Dennis L Cooper et al. Br J Haematol. 2025 Mar.
No abstract available

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References

REFERENCES

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    1. Al‐Homsi AS, Cirrone F, Wo S, Cole K, Suarez‐Londono JA, Gardner SL, et al. PTCy, abatacept, and a short course of tacrolimus for GVHD prevention after haploidentical transplantation. Blood Adv. 2023;7(14):3604–3611.
    1. Xie Y, Parekh J, Tang Z, Wu D, Wu X. Donor‐specific antibodies and primary graft failure in allogeneic hematopoietic stem cell transplantation: a systematic review and meta‐analysis. Transplant Cell Ther. 2021;27(8):687.e1–687.e7.
    1. Ciurea SO, Cao K, Fernandez‐Vina M, Kongtim P, Malki MA, Fuchs E, et al. The European Society for Blood and Marrow Transplantation (EBMT) consensus guidelines for the detection and treatment of donor‐specific anti‐HLA antibodies (DSA) in Haploidentical hematopoietic cell transplantation. Bone Marrow Transplant. 2018;53(5):521–534.
    1. Liu J, Zhao XY, Xu LP, Zhang XH, Wang Y, Mo XD, et al. The impact of donor‐specific anti‐HLA antibody levels on primary poor graft function and graft rejection in rituximab desensitized haploidentical stem cell transplantation. HLA. 2024;103(1):e15300.

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