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Review
. 2025 Feb;53(2):3000605251315353.
doi: 10.1177/03000605251315353.

Heat stroke with sepsis: A case report and review of the literature

Affiliations
Review

Heat stroke with sepsis: A case report and review of the literature

Suyu Wei et al. J Int Med Res. 2025 Feb.

Abstract

Heat stroke, triggered by excessive heat exposure or intense physical activity, is a medical condition characterized by a rapid rise in core body temperature, central nervous system dysfunction and multiorgan failure. A patient presented with heat stroke and was unconscious. During treatment, we identified a range of complications, including shifted flora, coagulation abnormalities, liver damage and renal failure-indicating multiorgan dysfunction. We administered antibiotic therapy, blood purification and other comprehensive treatments, leading to the patient's recovery and subsequent discharge. For cases of heat stroke in an intensive care setting, clinicians must recognize the condition early and act swiftly to reduce body temperature. Additionally, the early use of antibiotics can help prevent microbial imbalance. For eligible patients, hemodialysis should be initiated promptly to manage renal complications effectively.

Keywords: Heat stroke; bacterial translocation; hemodepletion; multiorgan failure; septicemia.

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Conflict of interest statement

Declaration of conflicting interestThe authors declare that there are no conflicts of interest.

Figures

Figure 1.
Figure 1.
Patient computed tomography (CT) scans during hospitalization: (a) CT images on the day of admission; (b) CT images 3 days after admission and (c) CT images before discharge.

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