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Case Reports
. 2025 Jan 3:16:1.
doi: 10.25259/SNI_93_2024. eCollection 2025.

Pediatric subcutaneous nasal glial heterotopia

Moajeb Turki Alzahrani  1 , Balgess Abdullah Ajlan  2 , Alaa Samkari  3 , Afnan Mahfouz Samman  4
Affiliations
Case Reports

Pediatric subcutaneous nasal glial heterotopia

Moajeb Turki Alzahrani et al. Surg Neurol Int. .

Abstract

Background: Nasal glial heterotopias (NGHs) are benign lesions diagnosed at birth that are treated with complete surgical excision and have a low recurrence rate. The impact of the timing of resection on the patients' outcome remains unclear.

Case description: We report a case of pediatric midline subcutaneous extranasal glial heterotopia over the nasal bridge in a 4-day-old female newborn. At the age of 6 months, she underwent a complete surgical excision. Follow-up magnetic resonance imaging at 3 years showed no evidence of recurrence. A summary of the 19 published cases of the specific entity of purely subcutaneous extranasal glial heterotopia among the pediatrics age group in the literature is presented, and the timing of surgery in relation to outcome is discussed.

Conclusion: Our review revealed that surgery for NGH can be safely performed when the child is 6-12 months old, and the child should be followed probably until school age.

Keywords: Nasal cerebral heterotopia; Nasal glial heterotopia; Nasal glioma; Neuroglial heterotopia.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1:
Figure 1:
Extranasal mass over the nasion protruding more toward the left side. It was measuring 1.5 by 2 cm, firm in consistency, and had a small purplish hue on its surface but no telangiectatic vessels.
Figure 2:
Figure 2:
Magnetic resonance imaging showing extranasal lesion. (a) T2 axial and saggital images showing lesion isointense signal. (b) T1 axial and saggital images showing lesion isointense signal.
Figure 3:
Figure 3:
(a and b) Microscopic examination of hematoxylin and eosin (H&E x20) stain sections revealing fragments of alternating dense collagenous tissue and disorganized fibrillary glial tissue and mature astrocytes. (c) Immunohistochemistry (x20) study showing positive glial fibrillary acidic protein in the glial components of the lesion.
Figure 4:
Figure 4:
Postoperative picture taken at 3 years of age.
Figure 5:
Figure 5:
Postoperative magnetic resonance imaging showing no evidence of recurrunce at 3 years of age with mildy hypertropic scar. (a) T1 axial and saggital images. (b) T2 axial and saggital images.
See this image and copyright information in PMC

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