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. 2025 Jan 3;10(Pt 1):x241243.
doi: 10.1107/S2414314624012434. eCollection 2025 Jan.

4-Chloro-curcumin

Phuong-Truc T Pham  1 , Mamoun M Bader  2
Affiliations

4-Chloro-curcumin

Phuong-Truc T Pham et al. IUCrdata. .

Erratum in

  • Erratum: 4-Chloro-curcumin. Addendum.
    Pham PT, Bader MM. Pham PT, et al. IUCrdata. 2025 Aug 28;10(Pt 8):x250635. doi: 10.1107/S2414314625006352. eCollection 2025 Aug. IUCrdata. 2025. PMID: 40917534 Free PMC article.

Abstract

The title compound [systematic name: 4-chloro-5-hy-droxy-1,7-bis-(4-hy-droxy-3-meth-oxy-phen-yl)hepta-1,4,6-trien-3-one], C21H19ClO6, is close to planar, with a dihedral angle of 2.61 (7)° between the terminal phenyl groups and three intra-molecular O-H⋯O hydrogen bonds occur. In the crystal, the mol-ecules are linked into [201] chains by O-H⋯O hydrogen bonds and weak aromatic π-π stacking is also observed with a shortest centroid-centroid separation of 3.7279 (8) Å.

Keywords: crystal structure; curcumin derivative; hydrogen bonds.

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Figures

Figure 1
Figure 1
The mol­ecular structure of (I) showing 50% displacement ellipsoids. Hydrogen bonds are shown as dotted lines.
Figure 2
Figure 2
Part of a [20formula image] hydrogen-bonded chain in the structure of (I).
Figure 3
Figure 3
The UV/visible absorption spectrum of (I) dissolved in di­chloro­methane.
See this image and copyright information in PMC

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