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Review
. 2025 Jan 27:15:1503025.
doi: 10.3389/fneur.2024.1503025. eCollection 2024.

Intravenous push administration of anti-seizure medications

Raniah Aljadeed  1   2 , Brian W Gilbert  3 , Tallib Karaze  4 , Megan A Rech  5
Affiliations
Review

Intravenous push administration of anti-seizure medications

Raniah Aljadeed et al. Front Neurol. .

Abstract

Intravenous push (IVP) administration of anti-seizure medications is becoming increasingly popular among emergency departments. IVP administration eliminates the need for compounding and preparation by the pharmacy department, as well as the need to gather infusion materials or set up a patient's tubing and pump, all of which translate to faster drug administration. This is important given the time-sensitive nature of status epilepticus treatment. This review will discuss several anti-seizure medications, including phenytoin, fosphenytoin, valproic acid, levetiracetam, brivaracetam and lacosamide, for which evidence supports the safe and efficacious use of IV push administration.

Keywords: Antiepileptic drugs; antiseizure medications; intravenous push; seizure; status epilepticus.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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