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. 2025 Apr;21(4):197-198.
doi: 10.1038/s41574-025-01089-w.

Recent advances in treatments for congenital adrenal hyperplasia

Henrik Falhammar  1   2 , Svetlana Lajic  3   4   5 , Anna Nordenström  6   7
Affiliations

Recent advances in treatments for congenital adrenal hyperplasia

Henrik Falhammar et al. Nat Rev Endocrinol. 2025 Apr.
No abstract available

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Conflict of interest statement

Competing interests: H.F. has been an investigator for studies and received consultation fees from Neurocrine Inc., Spruce Bioscience Inc. and H. Lundbeck A/S. S.L. has received consultation fees from Merck and Immedica. A.N. declares no competing interests.

References

    1. Claahsen-van der Grinten, H. L. et al. Congenital adrenal hyperplasia-current insights in pathophysiology, diagnostics, and management. Endocr. Rev. 43, 91–159 (2022). - DOI - PubMed
    1. Auer, M. K., Nordenström, A., Lajic, S. & Reisch, N. Congenital adrenal hyperplasia. Lancet 401, 227–244 (2023). - DOI - PubMed
    1. Whitaker, M. J., Huatan, H. & Ross, R. J. Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm. Drug Deliv. Transl. Res. 13, 1–8 (2023). - DOI - PubMed
    1. Auchus, R. J. et al. Phase 3 trial of crinecerfont in adult congenital adrenal hyperplasia. N. Engl. J. Med. 391, 504–514 (2024). - DOI - PubMed - PMC
    1. Sarafoglou, K. et al. Phase 3 trial of crinecerfont in pediatric congenital adrenal hyperplasia. N. Engl. J. Med. 391, 493–503 (2024). - DOI - PubMed

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