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Review
. 2025;23(9):1009-1020.
doi: 10.2174/011570159X367968250117034551.

Evaluating Remimazolam for Procedural Sedation

Genevieve Monanian  1 , Brandon Yonel  1 , Deborah Rupert  2 , Alina Razak  1 , Michelle DeLemos  1 , Sergio D Bergese  1   3
Affiliations
Review

Evaluating Remimazolam for Procedural Sedation

Genevieve Monanian et al. Curr Neuropharmacol. 2025.

Abstract

Remimazolam, a novel short-acting benzodiazepine, has garnered interest in the realm of procedural sedation. Targeting a desired level of sedation requires a medication with both anesthetic and analgesic properties, particularly in non-operating room anesthetizing locations. Via gammaaminobutyric acid type A receptor agonism, Remimazolam has demonstrated organ-independent metabolism and rapid time to both onset and recovery and has efficacy for procedural sedation in clinical trials. This article provides a review of the current literature on the utility of remimazolam for procedural sedation.

Keywords: Remimazolam; analgesic properties; clinical trials; depressed consciousness.; procedural sedation; remimazolam.

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Conflict of interest statement

The authors declare no conflict of interest, financial or otherwise.

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