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. 1985 Apr;20(4):625-9.
doi: 10.1002/ajmg.1320200408.

Metacarpophalangeal pattern profile analysis in Sotos syndrome

M G Butler, F J Meaney, S Kittur, J H Hersh, L Hornstein

Metacarpophalangeal pattern profile analysis in Sotos syndrome

M G Butler et al. Am J Med Genet. 1985 Apr.

Erratum in

  • Am J Med Genet 1986 Aug;24(4):761

Abstract

The metacarpophalangeal pattern profile (MCPP) was analyzed on 16 Sotos syndrome patients. A mean Sotos syndrome profile was produced. Correlation studies confirm clinical homogeneity of Sotos syndrome individuals. Discriminant analysis of Sotos syndrome patients and normal individuals produces a function of two MCPP variables and age, which may provide a useful tool for diagnosis.

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Figures

Fig. 1
Fig. 1
Mean MCPP for 16 individuals with Sotos syndrome.
Fig. 2
Fig. 2
Histogram depicting normal and Sotos syndrome classification by discriminant analysis. D = −2.24 − 0.92(X8) + 0.41(X11) + 0.24(age in years).
See this image and copyright information in PMC

References

    1. Bloom AS, Reese A, Hersh JH, Podruch PE, Weisskopf B, Dinno N. Cognition in cerebral gigantism: Are the estimates of mental retardation too high? J Dev Behav Pediatr. 1983;4:250–252. - PubMed
    1. Butler MG, Kaler SG, Yu PL, Meaney FJ. Metacarpophalangeal pattern profile analysis in Prader-Willi syndrome. Clin Genet. 1982;22:315–320. - PMC - PubMed
    1. Enslein K, Ralston A, Wilf HS. Statistical Methods for Digital Computers. New York: John Wiley and Sons; 1977. pp. 76–95.
    1. Escobar V, Bixler D. The acrocephalosyndactyly syndromes: A metacarpophalangeal pattern profile analysis. Clin Genet. 1977;11:295–305. - PubMed
    1. Garn SM, Hertzog KP, Poznanski AK, Nagy JM. Metacarpophalangeal length in the evaluation of skeletal malformation. Radiology. 1972;105:375–381. - PubMed

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