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Comment
. 2025 Feb 11;58(2):268-270.
doi: 10.1016/j.immuni.2025.01.011. Epub 2025 Feb 11.

Bacterial translocation promotes trained immunity

Maria Francesca Viola  1 , Elvira Mass  2
Affiliations
Comment

Bacterial translocation promotes trained immunity

Maria Francesca Viola et al. Immunity. .

Abstract

Can bacteria that breach mucosal barriers drive long-lasting changes in immunity? In this issue of Immunity, Robles-Vera et al. describe how, in the context of colitis, bacteria breaching the intestinal barrier reprogram precursors in the bone marrow via Mincle-dependent signaling.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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